Ditropan and Novolog drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Ditropan (oxybutynin chloride) and Novolog (insulin aspart recombinant). Common drug interactions include somnolence among females and hypoglycaemia among males.

The phase IV clinical study analyzes what interactions people have when they take Ditropan and Novolog. It is created by eHealthMe based on reports of 91 people who take the same drugs from the FDA, and is updated regularly.

What is Ditropan?

Ditropan has active ingredients of oxybutynin chloride. It is often used in urge incontinence. eHealthMe is studying from 11,799 Ditropan users. Check the latest studies of Ditropan.

What is Novolog?

Novolog has active ingredients of insulin aspart recombinant. It is often used in diabetes. eHealthMe is studying from 56,160 Novolog users. Check the latest studies of Novolog.



On Jul, 15, 2026

91 people who take Ditropan and Novolog together, and have interactions are studied.

Ditropan and Novolog drug interactions.

What are the common drug interactions of Ditropan and Novolog, by gender? *:

female:

  1. Somnolence (a state of near-sleep, a strong desire for sleep)
  2. Tremor (trembling or shaking movements in one or more parts of your body)
  3. Vomiting
  4. Drug hypersensitivity
  5. Frustration (a form of poorly expressed anger)
  6. Stress
  7. Chronic kidney disease
  8. Drug ineffective
  9. Renal failure (kidney dysfunction)
  10. Vision blurred

male:

  1. Hypoglycaemia (deficiency of glucose in the bloodstream)
  2. Nausea (feeling of having an urge to vomit)
  3. Epilepsy (common and diverse set of chronic neurological disorders characterized by seizures)
  4. Syncope (loss of consciousness with an inability to maintain postural tone)
  5. Blood glucose fluctuation
  6. Chills (felling of cold)
  7. Convulsion (muscles contract and relax rapidly and repeatedly, resulting in an uncontrolled shaking of the body)
  8. Decreased appetite
  9. Hyperglycaemia (high blood sugar)
  10. Malaise (a feeling of general discomfort or uneasiness)

What are the common drug interactions of Ditropan and Novolog, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

  1. Diabetic ketoacidosis (diabetic ketoacidosis (dka) is high concentrations of ketone bodies)
  2. Blood calcium decreased
  3. Blood creatinine decreased
  4. Blood pressure decreased
  5. Blood urea decreased
  6. Dehydration (dryness resulting from the removal of water)
  7. Dysphonia (speech disorder attributable to a disorder of phonation)
  8. Extravasation (leakage of a fluid)
  9. Haematocrit decreased
  10. Haemoglobin decreased

40-49:

  1. Chronic kidney disease
  2. Renal injury (kidney injury)
  3. Altered state of consciousness (altered state of mind)
  4. Crepitations (noises are produced by the rubbing of parts one against the other)
  5. Discomfort
  6. Dyspnoea (difficult or laboured respiration)
  7. Flatulence (flatus expelled through the anus)
  8. Irritability
  9. Nausea (feeling of having an urge to vomit)
  10. Nephrogenic anaemia (anaemia due to kidney disease)

50-59:

  1. Rectal haemorrhage (bleeding from anus)
  2. Abdominal pain
  3. Abdominal tenderness
  4. Adverse drug reaction
  5. Alopecia (absence of hair from areas of the body)
  6. Anxiety
  7. Aphasia (damage to the parts of the brain that control language)
  8. Arthralgia (joint pain)
  9. Asthenia (weakness)
  10. Atrophy (wasting away of a part of the body)

60+:

  1. Decreased appetite
  2. Hypertension (high blood pressure)
  3. Muscle spasms (muscle contraction)
  4. Somnolence (a state of near-sleep, a strong desire for sleep)
  5. Tremor (trembling or shaking movements in one or more parts of your body)
  6. Frustration (a form of poorly expressed anger)
  7. Stress
  8. Drug hypersensitivity
  9. Chronic kidney disease
  10. Drug ineffective

What are the existing conditions these people have? *

  1. High Blood Pressure: 23 people, 25.27%
  2. Pain: 17 people, 18.68%
  3. Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 12 people, 13.19%
  4. Multiple Sclerosis (a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath): 10 people, 10.99%
  5. Type 2 Diabetes: 10 people, 10.99%
  6. Quit Smoking: 10 people, 10.99%
  7. Osteoarthritis (a joint disease caused by cartilage loss in a joint): 9 people, 9.89%
  8. Stress And Anxiety: 9 people, 9.89%
  9. Atrial Fibrillation/flutter (atrial fibrillation and flutter are abnormal heart rhythms in which the atria, or upper chambers of the heart, are out of sync with the ventricles): 9 people, 9.89%
  10. Constipation: 8 people, 8.79%

* Approximation only. Some reports may have incomplete information.

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Ditropan and Novolog:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Ditropan:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Novolog:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Ditropan and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Novolog and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

How the study uses the data?

The study uses data from the FDA. It is based on oxybutynin chloride and insulin aspart recombinant (the active ingredients of Ditropan and Novolog, respectively), and Ditropan and Novolog (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

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