Ditropan and Zelnorm drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Ditropan (oxybutynin chloride) and Zelnorm (tegaserod maleate). Common drug interactions include alanine aminotransferase increased among females and cerebral atrophy among males.

The phase IV clinical study analyzes what interactions people have when they take Ditropan and Zelnorm. It is created by eHealthMe based on reports of 27 people who take the same drugs from the FDA, and is updated regularly.

What is Ditropan?

Ditropan has active ingredients of oxybutynin chloride. It is often used in urge incontinence. eHealthMe is studying from 11,799 Ditropan users. Check the latest studies of Ditropan.

What is Zelnorm?

Zelnorm has active ingredients of tegaserod maleate. eHealthMe is studying from 7,261 Zelnorm users. Check the latest studies of Zelnorm.

On Jul, 20, 2026

27 people who take Ditropan and Zelnorm together, and have interactions are studied.

What are the common drug interactions of Ditropan and Zelnorm, by gender? *:

female:

Alanine aminotransferase increased
Aspartate aminotransferase increased
Asthenia (weakness)
Asthma
Balance disorder
Depression
Diabetes mellitus (diabetes, caused by a deficiency of the pancreatic hormone insulin)
Diarrhoea
Diarrhoea haemorrhagic (bloody diarrhoea)
Drug ineffective

male:

Cerebral atrophy (decrement in size of brain)
Fatigue (feeling of tiredness)
Atrial flutter (an abnormal heart rhythm that occurs in the atria of the heart)
Atrial tachycardia (rhythm disturbance that arises in the atria)
Balance disorder
Brain stem haemorrhage (bleeding into structures of brain stem)
Cardiac failure
Carotid arteriosclerosis (plaque deposition in artery)
Cerebrovascular accident (sudden death of some brain cells due to lack of oxygen when the blood flow to the brain is impaired by blockage or rupture)
Coronary artery disease (plaque building up along the inner walls of the arteries of the heart, which narrows the arteries and restricts blood flow to the heart)

What are the common drug interactions of Ditropan and Zelnorm, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

Dyspnoea (difficult or laboured respiration)
Throat tightness
Hypersensitivity
Infusion related reaction
Pallor
Respiratory distress (difficulty in breathing)
Wheezing (a high-pitched whistling sound made while you breath)

40-49:

Abdominal distension
Abdominal pain
Bone cyst
Cerebrovascular accident (sudden death of some brain cells due to lack of oxygen when the blood flow to the brain is impaired by blockage or rupture)
Constipation
Diabetes mellitus inadequate control
Dizziness
Dyspnoea (difficult or laboured respiration)
Exostosis (formation of new bone on the surface of a bone)
Foot deformity (functional disability of foot)

50-59:

Tinnitus (a ringing in the ears)
Diarrhoea haemorrhagic (bloody diarrhoea)
Abdominal pain
Abdominal tenderness
Blood potassium decreased
Chest pain
Colitis (inflammation of colon)
Colitis ischaemic (due to infection of intestine impaired blood supply to colon)
Diarrhoea
Extrasystoles

60+:

Dizziness
Balance disorder
Dyspnoea (difficult or laboured respiration)
Hypertension (high blood pressure)
Intervertebral disc disorder (spinal disc disorder)
Spinal disorder (disease of spine a back bone)
Arrhythmia (irregular heartbeat)
Atrial fibrillation (fibrillation of the muscles of the atria of the heart)
Atrial flutter (an abnormal heart rhythm that occurs in the atria of the heart)
Atrial tachycardia (rhythm disturbance that arises in the atria)

What are the existing conditions these people have? *

Irritable Bowel Syndrome: 6 people, 22.22%
Pain: 4 people, 14.81%
Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 3 people, 11.11%
Depression: 3 people, 11.11%
Constipation: 3 people, 11.11%
Asthma: 3 people, 11.11%
Pain In Extremity: 2 people, 7.41%
High Blood Cholesterol: 2 people, 7.41%
Back Pain: 2 people, 7.41%

* Approximation only. Some reports may have incomplete information.

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