Divalproex and Claritin drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Divalproex (divalproex sodium) and Claritin (loratadine). Common drug interactions include spinal disorder among females and seizure among males.

The phase IV clinical study analyzes what interactions people have when they take Divalproex and Claritin. It is created by eHealthMe based on reports of 100 people who take the same drugs from the FDA, and is updated regularly.

What is Divalproex?

Divalproex has active ingredients of divalproex sodium. It is often used in bipolar disorder. eHealthMe is studying from 14,063 Divalproex users. Check the latest studies of Divalproex.

What is Claritin?

Claritin has active ingredients of loratadine. It is often used in allergies. eHealthMe is studying from 77,316 Claritin users. Check the latest studies of Claritin.

On Aug, 05, 2026

100 people who take Divalproex and Claritin together, and have interactions are studied.

Divalproex and Claritin drug interactions.

What are the common drug interactions of Divalproex and Claritin, by gender? *:

female:

Spinal disorder (disease of spine a back bone)
Head injury
Insomnia (sleeplessness)
Malaise (a feeling of general discomfort or uneasiness)
Dizziness
Chills (felling of cold)
Syncope (loss of consciousness with an inability to maintain postural tone)
Bronchitis (inflammation of the mucous membrane in the bronchial tubes)
Cardiac disorder
Dermatitis contact (skin reaction (dermatitis) resulting from exposure to allergens)

male:

Seizure (abnormal excessive or synchronous neuronal activity in the brain)
Chronic kidney disease
Blood iron decreased
Muscle spasms (muscle contraction)
Nephrolithiasis (calculi in the kidneys)
Rib fracture
Affective disorder (mental disorder)
Drug ineffective
Feeling hot
Peripheral coldness

What are the common drug interactions of Divalproex and Claritin, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

Activities of daily living impaired
Asthma
Cognitive disorder (mental health disorders affects learning, memory, perception, and problem solving)
Constipation
Discomfort
Drug withdrawal syndrome (interfere with normal social, occupational, or other functioning. are not due to another medical condition, drug use, or discontinuation)
Dysarthria (speech disorder)
Dystonia (abnormal muscle tone)
Kyphosis (a condition of over-curvature of the thoracic vertebrae (upper back))
Lethargy (tiredness)

10-19:

Seizure (abnormal excessive or synchronous neuronal activity in the brain)
Diarrhoea
Retching (strong involuntary effort to vomit)
Surgery
Balance disorder
Fall
Hypophagia (reduced food intake)
Restlessness (not able to rest)
Vomiting
Wrist fracture

20-29:

Febrile neutropenia (fever with reduced white blood cells)
Acute respiratory failure
Alanine aminotransferase increased
Anhedonia (inability to experience pleasure from activities usually found enjoyable)
Anxiety
Aspartate aminotransferase increased
Bile duct stone
Blood culture positive
Cholecystitis chronic (long lasting infection of gallbladder)
Clostridium difficile colitis (inflammation of colon by clostridium difficile bacteria infection)

30-39:

Hyperglycaemia (high blood sugar)
Myositis (inflammation of the muscles)
Post procedural haemorrhage (post procedural bleeding)
Procedural pain
Blood glucose decreased
Chronic kidney disease
Diabetes mellitus inadequate control
Gastrooesophageal reflux disease (stomach contents (food or liquid) leak backwards from the stomach into the oesophagus)
Nephrogenic anaemia (anaemia due to kidney disease)
Renal failure (kidney dysfunction)

40-49:

Anxiety
Chronic kidney disease
Fatigue (feeling of tiredness)
Pain
Affective disorder (mental disorder)
Drug ineffective
Feeling hot
Peripheral coldness
Suicidal ideation
Diarrhoea

50-59:

Obesity (having too much body fat)
Osteoporosis (bones weak and more likely to break)
Pain
Pneumonia
Stress urinary incontinence (leak urine with things like coughing, sneezing or exercise)
Tachycardia paroxysmal (a form of tachycardia which begins and ends in an acute (or paroxysmal) manner)
Type 2 diabetes mellitus
Diabetic nephropathy (diabetic kidney disease)
Diabetic neuropathy (neuropathic disorders that are associated with diabetes mellitus)
Renal failure (kidney dysfunction)

60+:

Fall
Cough
Cardiac disorder
Dermatitis contact (skin reaction (dermatitis) resulting from exposure to allergens)
Immune system disorder
Infection
Infusion site discomfort
Infusion site swelling
Sinusitis (inflammation of sinus)
Swelling

What are the existing conditions these people have? *

Immunodeficiency Common Variable: 19 people, 19.00%
High Blood Pressure: 16 people, 16.00%
Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 16 people, 16.00%
Depression: 10 people, 10.00%
Hypersensitivity: 10 people, 10.00%
Hypergammaglobulinaemia (elevated levels of gamma globulin): 9 people, 9.00%
Diabetes: 8 people, 8.00%
Pain: 8 people, 8.00%
Seizures (abnormal excessive or synchronous neuronal activity in the brain): 8 people, 8.00%
High Blood Cholesterol: 7 people, 7.00%

* Approximation only. Some reports may have incomplete information.

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