Divalproex and Erythromycin drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Divalproex (divalproex sodium) and Erythromycin (erythromycin). Common drug interactions include pulmonary embolism among females and chronic kidney disease among males.

The phase IV clinical study analyzes what interactions people have when they take Divalproex and Erythromycin. It is created by eHealthMe based on reports of 26 people who take the same drugs from the FDA, and is updated regularly.

What is Divalproex?

Divalproex has active ingredients of divalproex sodium. It is often used in bipolar disorder. eHealthMe is studying from 14,063 Divalproex users. Check the latest studies of Divalproex.

What is Erythromycin?

Erythromycin has active ingredients of erythromycin. It is often used in acne. eHealthMe is studying from 12,563 Erythromycin users. Check the latest studies of Erythromycin.

On Aug, 11, 2026

26 people who take Divalproex and Erythromycin together, and have interactions are studied.

Divalproex and Erythromycin drug interactions.

What are the common drug interactions of Divalproex and Erythromycin, by gender? *:

female:

Pulmonary embolism (blockage of the main artery of the lung)
Weakness
Cardio-respiratory arrest (sudden dysfunction of heart and lungs)
Chronic kidney disease
Respiratory disorder (respiratory disease)
Renal failure (kidney dysfunction)
Renal tubular necrosis (death of kidney tubules)
Back pain
Emotional distress
Muscle rigidity (muscle stiffness)

male:

Chronic kidney disease
Memory impairment
Pain
Rhinovirus infection
Nasopharyngitis (inflammation of the nasopharynx)
Pneumonia
Renal failure (kidney dysfunction)
Renal injury (kidney injury)
Hyperparathyroidism secondary (an abnormally high concentration of parathyroid hormone in the blood, resulting in weakening of the bones through loss of calcium-secondary)
Injection site erythema (redness at injection site)

What are the common drug interactions of Divalproex and Erythromycin, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

Abasia (inability to walk)
Bone density decreased
Chest pain
Injection site bruising
Injection site erythema (redness at injection site)
Memory impairment
Nasopharyngitis (inflammation of the nasopharynx)
Oedema peripheral (superficial swelling)
Pain
Pneumonia

40-49:

Pulmonary embolism (blockage of the main artery of the lung)
Weakness
Cardio-respiratory arrest (sudden dysfunction of heart and lungs)
Respiratory disorder (respiratory disease)
Memory impairment
Nasopharyngitis (inflammation of the nasopharynx)
Pneumonia
Chronic kidney disease
Pain
Abdominal pain

50-59:

Chronic kidney disease
Renal failure (kidney dysfunction)
Renal injury (kidney injury)
Renal tubular necrosis (death of kidney tubules)
Death
Nephrogenic anaemia (anaemia due to kidney disease)

60+:

Anorexia (eating disorder characterized by immoderate food restriction and irrational fear of gaining weight)
Apraxia (disorder that affects a person's ability to organize the movements of the muscles used in speech)
Coma (state of unconsciousness lasting more than six hours)
Confusion
Cystitis (inflammation of the wall of the bladder)
Dehydration (dryness resulting from the removal of water)
Depression
Drug ineffective
Drug toxicity
Drug withdrawal syndrome (interfere with normal social, occupational, or other functioning. are not due to another medical condition, drug use, or discontinuation)

What are the existing conditions these people have? *

Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 10 people, 38.46%
High Blood Pressure: 8 people, 30.77%
Stress And Anxiety: 6 people, 23.08%
Depression: 6 people, 23.08%
High Blood Cholesterol: 5 people, 19.23%
Seizures (abnormal excessive or synchronous neuronal activity in the brain): 5 people, 19.23%
Cardiac Disorder: 5 people, 19.23%
Pain: 5 people, 19.23%
Inflammation: 4 people, 15.38%
Osteoporosis (bones weak and more likely to break): 4 people, 15.38%

* Approximation only. Some reports may have incomplete information.

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