Divalproex and Ms contin drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Divalproex (divalproex sodium) and Ms contin (morphine sulfate). Common drug interactions include chronic kidney disease among females and pain in extremity among males.

The phase IV clinical study analyzes what interactions people have when they take Divalproex and Ms contin. It is created by eHealthMe based on reports of 14 people who take the same drugs from the FDA, and is updated regularly.

What is Divalproex?

Divalproex has active ingredients of divalproex sodium. It is often used in bipolar disorder. eHealthMe is studying from 14,063 Divalproex users. Check the latest studies of Divalproex.

What is Ms contin?

Ms contin has active ingredients of morphine sulfate. It is often used in pain. eHealthMe is studying from 69,289 Ms contin users. Check the latest studies of Ms contin.

On Jul, 28, 2026

14 people who take Divalproex and Ms contin together, and have interactions are studied.

Divalproex and Ms contin drug interactions.

What are the common drug interactions of Divalproex and Ms Contin, by gender? *:

female:

Chronic kidney disease
Abdominal pain
Alanine aminotransferase increased
Alopecia (absence of hair from areas of the body)
Anhedonia (inability to experience pleasure from activities usually found enjoyable)
Anxiety
Aspartate aminotransferase increased
Confusional state
Decreased activity
Emotional distress

male:

Pain in extremity
Chest pain
Disability
Disturbance in attention
Dyspnoea paroxysmal nocturnal (respiratory distress that awakens patients from sleep)
Dysstasia (difficulty in standing)
Dysuria (painful or difficult urination)
Erectile dysfunction
Gait disturbance
Hyperhidrosis (abnormally increased sweating)

What are the common drug interactions of Divalproex and Ms Contin, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

Breath sounds
Cyanosis (lack of oxygen in body leads to blue appearance of skin ,mucous membrane nails)
Unresponsive to stimuli

30-39:

Chronic kidney disease
Nephrogenic anaemia (anaemia due to kidney disease)
Renal failure (kidney dysfunction)
Renal injury (kidney injury)

40-49:

Asthenia (weakness)
Back disorder
Cardiac disorder
Chest discomfort
Chest pain
Cough
Disability
Disturbance in attention
Drug dependence
Dyspnoea (difficult or laboured respiration)

50-59:

Cough
Decreased appetite
Diabetes mellitus (diabetes, caused by a deficiency of the pancreatic hormone insulin)
Diabetic complication
Dyspnoea (difficult or laboured respiration)
Exostosis (formation of new bone on the surface of a bone)
Fatigue (feeling of tiredness)
Headache (pain in head)
Hernia (hernia happens when part of an internal organ or tissue bulges through a weak area of muscle)
Hot flush (sudden feelings of heat)

60+:

Anhedonia (inability to experience pleasure from activities usually found enjoyable)
Anxiety
Chronic kidney disease
Decreased activity
Emotional distress
Osteoporosis (bones weak and more likely to break)
Renal impairment (severely reduced kidney function)
Wrist fracture

What are the existing conditions these people have? *

Multiple Myeloma (cancer of the plasma cells): 3 people, 21.43%
Back Pain: 2 people, 14.29%
Schizophrenia (a mental disorder characterized by a breakdown of thought processes): 1 person, 7.14%
Renal Cell Carcinoma (a kidney cancer): 1 person, 7.14%
Hiv Infection: 1 person, 7.14%
Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 1 person, 7.14%
Depression: 1 person, 7.14%

* Approximation only. Some reports may have incomplete information.

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