Divalproex and Nayzilam drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Divalproex (divalproex sodium) and Nayzilam (midazolam). Common drug interactions include seizure among females and seizure among males.

The phase IV clinical study analyzes what interactions people have when they take Divalproex and Nayzilam. It is created by eHealthMe based on reports of 13 people who take the same drugs from the FDA, and is updated regularly.

What is Divalproex?

Divalproex has active ingredients of divalproex sodium. It is often used in bipolar disorder. eHealthMe is studying from 14,063 Divalproex users. Check the latest studies of Divalproex.

What is Nayzilam?

Nayzilam has active ingredients of midazolam. eHealthMe is studying from 677 Nayzilam users. Check the latest studies of Nayzilam.

On Jul, 26, 2026

13 people who take Divalproex and Nayzilam together, and have interactions are studied.

Divalproex and Nayzilam drug interactions.

What are the common drug interactions of Divalproex and Nayzilam, by gender? *:

female:

Seizure (abnormal excessive or synchronous neuronal activity in the brain)
Postictal state
Death
Diarrhoea
Drug ineffective
Lethargy (tiredness)
Speech disorder
Vomiting
Abnormal behaviour
Blood iron increased

male:

Seizure (abnormal excessive or synchronous neuronal activity in the brain)
Infusion site pain
Pneumonia
Respiratory failure (inadequate gas exchange by the respiratory system)
Sepsis (a severe blood infection that can lead to organ failure and death)
Somnolence (a state of near-sleep, a strong desire for sleep)
Viral infection
Abdominal pain
Craniocerebral injury (injury to cranium and brain)
Discomfort

What are the common drug interactions of Divalproex and Nayzilam, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

Seizure (abnormal excessive or synchronous neuronal activity in the brain)
Diarrhoea
Infusion site pain
Vomiting
Abdominal pain
Discomfort
Dry skin
Gastrointestinal pain
Hospitalisation
Irritability

20-29:

Blood iron increased
Decreased appetite
Seizure (abnormal excessive or synchronous neuronal activity in the brain)
Weight decreased

30-39:

n/a

40-49:

n/a

50-59:

Overdose
Pyrexia (fever)
Seizure (abnormal excessive or synchronous neuronal activity in the brain)
Urinary tract infection
Abnormal behaviour
Hallucinations, mixed (sensations that appear real but are created by your mind -mixed)
Infection
Influenza

60+:

Postictal state
Seizure (abnormal excessive or synchronous neuronal activity in the brain)
Death
Drug ineffective
Lethargy (tiredness)
Speech disorder

What are the existing conditions these people have? *

Seizures (abnormal excessive or synchronous neuronal activity in the brain): 10 people, 76.92%
Hypersensitivity: 3 people, 23.08%
Lennox-Gastaut Syndrome (epilepsy characterized by frequent seizures and different seizure types): 3 people, 23.08%
Carnitine Deficiency: 2 people, 15.38%
Nausea (feeling of having an urge to vomit): 2 people, 15.38%
Constipation: 2 people, 15.38%
Epilepsy (common and diverse set of chronic neurological disorders characterized by seizures): 2 people, 15.38%
Hypothyroidism (abnormally low activity of the thyroid gland, resulting in retardation of growth and mental development): 2 people, 15.38%
Urinary Tract Infection: 1 person, 7.69%
Agitation (state of anxiety or nervous excitement): 1 person, 7.69%

* Approximation only. Some reports may have incomplete information.

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