Dolutegravir and Voriconazole drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Dolutegravir (dolutegravir) and Voriconazole (voriconazole). Common drug interactions include escherichia urinary tract infection among females and diarrhoea among males.

The phase IV clinical study analyzes what interactions people have when they take Dolutegravir and Voriconazole. It is created by eHealthMe based on reports of 35 people who take the same drugs from the FDA, and is updated regularly.

What is Dolutegravir?

Dolutegravir has active ingredients of dolutegravir. eHealthMe is studying from 7,071 Dolutegravir users. Check the latest studies of Dolutegravir.

What is Voriconazole?

Voriconazole has active ingredients of voriconazole. It is often used in aspergillosis. eHealthMe is studying from 21,706 Voriconazole users. Check the latest studies of Voriconazole.

On Aug, 05, 2026

35 people who take Dolutegravir and Voriconazole together, and have interactions are studied.

Dolutegravir and Voriconazole drug interactions.

What are the common drug interactions of Dolutegravir and Voriconazole, by gender? *:

female:

Escherichia urinary tract infection (urinary tract infection by escherichia coli)
Viral oesophagitis (inflammation of the oesophagus caused by viral infection)
Oesophagitis (inflammation of oesophagus)

male:

Diarrhoea
Respiratory failure (inadequate gas exchange by the respiratory system)
Disease recurrence
Dysphagia (a condition in which swallowing is difficult or painful)
Pyrexia (fever)
Cd4 lymphocytes decreased
Central nervous system lesion (an abnormality in tissue of brain or spinal cord)
Cerebral venous thrombosis (clot in brains venous blood system)
Emotional distress
Encephalitis (inflammation of the brain)

What are the common drug interactions of Dolutegravir and Voriconazole, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

Escherichia urinary tract infection (urinary tract infection by escherichia coli)
Viral oesophagitis (inflammation of the oesophagus caused by viral infection)
Oesophagitis (inflammation of oesophagus)
Pseudoporphyria (skin changes consistent with one of the porphyrias, but laboratory tests do not detect significant abnormalities)

40-49:

Diarrhoea
Respiratory failure (inadequate gas exchange by the respiratory system)
Dyspnoea (difficult or laboured respiration)
General physical health deterioration (weak health status)
Oedema (fluid collection in tissue)
Pancytopenia (medical condition in which there is a reduction in the number of red and white blood cells, as well as platelets)
Respiratory gas exchange disorder (gas exchange disease of respiratory system)
Drug ineffective
Dysphagia (a condition in which swallowing is difficult or painful)
Blood hiv rna increased

50-59:

Disease recurrence
Hydrocephalus (water on the brain)
Hypokalaemia (low potassium)
Lethargy (tiredness)
Mental disorder (a psychological term for a mental or behavioural pattern or anomaly that causes distress or disability)
Mental status changes (general changes in brain function, such as confusion, amnesia (memory loss), loss of alertness, loss of orientation)
Pyrexia (fever)
Seizure (abnormal excessive or synchronous neuronal activity in the brain)

60+:

Encephalitis (inflammation of the brain)
Meningitis cryptococcal (bacterial inflammation of the protective membranes covering the brain and spinal cord, known collectively as the meninges)
Hydrocephalus (water on the brain)
Mental status changes (general changes in brain function, such as confusion, amnesia (memory loss), loss of alertness, loss of orientation)
Seizure (abnormal excessive or synchronous neuronal activity in the brain)
Antiviral drug level below therapeutic
Blood hiv rna increased
Brain herniation (brain herniation is a potentially deadly side effect of very high intracranial pressure that occurs when a part of the brain is squeezed across structures within the skull)
Brain oedema (excess accumulation of fluid in the intracellular or extracellular spaces of the brain)
Brain stem haemorrhage (bleeding into structures of brain stem)

What are the existing conditions these people have? *

Hiv Infection: 15 people, 42.86%
Meningitis Cryptococcal (bacterial inflammation of the protective membranes covering the brain and spinal cord, known collectively as the meninges): 10 people, 28.57%
Affective Disorder (mental disorder): 5 people, 14.29%
Bacterial Infection: 4 people, 11.43%
Acquired Immunodeficiency Syndrome (disease of the human immune system caused by the human immunodeficiency virus (hiv)): 3 people, 8.57%
Bone Marrow Conditioning Regimen: 3 people, 8.57%
Pneumonia Cryptococcal (pneumonia caused by cryptococcal infection): 3 people, 8.57%
Pneumonia Bacterial (pneumonia associated with bacterial infection): 3 people, 8.57%
Pneumonia: 3 people, 8.57%
Acute Hiv Infection: 2 people, 5.71%

* Approximation only. Some reports may have incomplete information.

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