Donepezil and Celexa drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Donepezil (donepezil hydrochloride) and Celexa (citalopram hydrobromide). Common drug interactions include cerebrovascular accident among females and pneumonia among males.

The phase IV clinical study analyzes what interactions people have when they take Donepezil and Celexa. It is created by eHealthMe based on reports of 97 people who take the same drugs from the FDA, and is updated regularly.

What is Donepezil?

Donepezil has active ingredients of donepezil hydrochloride. It is often used in dementia. eHealthMe is studying from 24,564 Donepezil users. Check the latest studies of Donepezil.

What is Celexa?

Celexa has active ingredients of citalopram hydrobromide. It is often used in depression. eHealthMe is studying from 56,390 Celexa users. Check the latest studies of Celexa.

On Jul, 17, 2026

97 people who take Donepezil and Celexa together, and have interactions are studied.

What are the common drug interactions of Donepezil and Celexa, by gender? *:

female:

Cerebrovascular accident (sudden death of some brain cells due to lack of oxygen when the blood flow to the brain is impaired by blockage or rupture)
Dehydration (dryness resulting from the removal of water)
Drug hypersensitivity
Dysphonia (speech disorder attributable to a disorder of phonation)
Headache (pain in head)
Malaise (a feeling of general discomfort or uneasiness)
Malignant melanoma (skin cancer rises from melancytes)
Sinusitis (inflammation of sinus)
Lung neoplasm malignant (cancer tumour of lung)
Nephrogenic anaemia (anaemia due to kidney disease)

male:

Pneumonia
Fatigue (feeling of tiredness)
Cataract (clouding of the lens inside the eye)
Cerebrovascular accident (sudden death of some brain cells due to lack of oxygen when the blood flow to the brain is impaired by blockage or rupture)
Hypercalcaemia (elevated calcium (ca+) level in the blood)
Myalgia (muscle pain)
Pain
Visual field defect
Apnoea (suspension of external breathing)
Bruxism (habitual grinding of the teeth, typically during sleep)

What are the common drug interactions of Donepezil and Celexa, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

n/a

50-59:

Renal failure (kidney dysfunction)
Renal mass (mass in kidney)
Road traffic accident
Tibia fracture (fracture of lower leg bone)
Vitamin b12 decreased
Vitamin d decreased
Chest pain
Arthritis (form of joint disorder that involves inflammation of one or more joints)
Pulmonary embolism (blockage of the main artery of the lung)
Nasopharyngitis (inflammation of the nasopharynx)

60+:

Fatigue (feeling of tiredness)
Nausea (feeling of having an urge to vomit)
Cataract (clouding of the lens inside the eye)
Cerebrovascular accident (sudden death of some brain cells due to lack of oxygen when the blood flow to the brain is impaired by blockage or rupture)
Death
Hypercalcaemia (elevated calcium (ca+) level in the blood)
Myalgia (muscle pain)
Visual field defect
Apnoea (suspension of external breathing)
Bruxism (habitual grinding of the teeth, typically during sleep)

What are the existing conditions these people have? *

Multiple Sclerosis (a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath): 12 people, 12.37%
Parkinson's Disease: 10 people, 10.31%
Immunodeficiency Common Variable: 10 people, 10.31%
Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 10 people, 10.31%
Multiple Myeloma (cancer of the plasma cells): 9 people, 9.28%
Prostate Cancer: 5 people, 5.15%
High Blood Cholesterol: 5 people, 5.15%
Hallucinations (sensations that appear real but are created by your mind): 5 people, 5.15%
Delusion (a false belief or opinion): 5 people, 5.15%

* Approximation only. Some reports may have incomplete information.

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