Doryx and Furosemide drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Doryx (doxycycline hyclate) and Furosemide (furosemide). Common drug interactions include pancreatitis among females and cellulitis among males.

The phase IV clinical study analyzes what interactions people have when they take Doryx and Furosemide. It is created by eHealthMe based on reports of 17 people who take the same drugs from the FDA, and is updated regularly.

What is Doryx?

Doryx has active ingredients of doxycycline hyclate. It is often used in acne. eHealthMe is studying from 901 Doryx users. Check the latest studies of Doryx.

What is Furosemide?

Furosemide has active ingredients of furosemide. It is often used in fluid retention. eHealthMe is studying from 316,095 Furosemide users. Check the latest studies of Furosemide.



On Jul, 06, 2026

17 people who take Doryx and Furosemide together, and have interactions are studied.

Doryx and Furosemide drug interactions.

What are the common drug interactions of Doryx and Furosemide, by gender? *:

female:

  1. Pancreatitis (inflammation of pancreas)
  2. Pancytopenia (medical condition in which there is a reduction in the number of red and white blood cells, as well as platelets)
  3. Renal impairment (severely reduced kidney function)
  4. Splenomegaly (enlargement of spleen)
  5. Thrombosis (formation of a blood clot inside a blood vessel)
  6. Transient ischaemic attack (a transient episode of neurologic dysfunction caused by ischemia (loss of blood flow))
  7. Abdominal discomfort
  8. Chronic kidney disease
  9. Constipation
  10. Diarrhoea

male:

  1. Cellulitis (infection under the skin)
  2. Sepsis (a severe blood infection that can lead to organ failure and death)
  3. Atrioventricular block first degree (heart block first degree)
  4. Benign prostatic hyperplasia (benign enlargement of the prostate)
  5. Bladder obstruction
  6. Blister (small pocket of fluid within the upper layers of the skin caused by forceful rubbing (friction), burning, freezing, chemical exposure)
  7. Blood potassium increased
  8. Cardiac disorder
  9. Cardiac failure congestive
  10. Cardiac murmur (an heart sound in valve abnormality)

What are the common drug interactions of Doryx and Furosemide, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

n/a

50-59:

  1. Cellulitis (infection under the skin)
  2. Sepsis (a severe blood infection that can lead to organ failure and death)
  3. Lethargy (tiredness)
  4. Methaemoglobinaemia (a disorder characterized by the presence of a higher than normal level of methemoglobin in blood)
  5. Pancytopenia (medical condition in which there is a reduction in the number of red and white blood cells, as well as platelets)
  6. Splenomegaly (enlargement of spleen)

60+:

  1. Constipation
  2. Nausea (feeling of having an urge to vomit)
  3. Arthralgia (joint pain)
  4. Asthenia (weakness)
  5. Atelectasis (partial or complete collapse of the lung)
  6. Atrioventricular block first degree (heart block first degree)
  7. Benign prostatic hyperplasia (benign enlargement of the prostate)
  8. Bladder obstruction
  9. Blister (small pocket of fluid within the upper layers of the skin caused by forceful rubbing (friction), burning, freezing, chemical exposure)
  10. Blood potassium increased

What are the existing conditions these people have? *

  1. Upper Respiratory Tract Infection: 7 people, 41.18%
  2. Depression: 7 people, 41.18%
  3. Joint Pain: 6 people, 35.29%
  4. Constipation: 6 people, 35.29%
  5. Insomnia (sleeplessness): 6 people, 35.29%
  6. Diarrhea: 6 people, 35.29%
  7. Muscle Aches (muscle pain): 6 people, 35.29%
  8. Muscle Spasticity (tight or stiff muscles and an inability to control those muscles): 6 people, 35.29%
  9. Oedema Peripheral (superficial swelling): 6 people, 35.29%
  10. Deep Venous Thrombosis (blood clot in a major vein that usually develops in the legs and/or pelvis): 6 people, 35.29%

* Approximation only. Some reports may have incomplete information.

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Doryx and Furosemide:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Doryx:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Furosemide:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Doryx and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Furosemide and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Related publications that referenced our studies


How the study uses the data?

The study uses data from the FDA. It is based on doxycycline hyclate and furosemide (the active ingredients of Doryx and Furosemide, respectively), and Doryx and Furosemide (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



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