Dotarem and Morphine drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Dotarem (gadoterate meglumine) and Morphine (morphine sulfate). Common drug interactions include bone pain among females and seizure among males.

The phase IV clinical study analyzes what interactions people have when they take Dotarem and Morphine. It is created by eHealthMe based on reports of 24 people who take the same drugs from the FDA, and is updated regularly.

What is Dotarem?

Dotarem has active ingredients of gadoterate meglumine. eHealthMe is studying from 2,749 Dotarem users. Check the latest studies of Dotarem.

What is Morphine?

Morphine has active ingredients of morphine sulfate. It is often used in pain. eHealthMe is studying from 182,913 Morphine users. Check the latest studies of Morphine.

On Jul, 23, 2026

24 people who take Dotarem and Morphine together, and have interactions are studied.

What are the common drug interactions of Dotarem and Morphine, by gender? *:

female:

Bone pain
Bacteraemia (presence of bacteria in the blood)
Device failure
Hypoglycaemia (deficiency of glucose in the bloodstream)
Hypotension (abnormally low blood pressure)
Small intestinal obstruction (blockage in small intestine)
Anaphylactic reaction (serious allergic reaction)
Nausea (feeling of having an urge to vomit)
Vomiting
Abdominal pain

male:

Seizure (abnormal excessive or synchronous neuronal activity in the brain)
Adverse event
Cytokine release syndrome (immediate complication occurring with the use of anti-t cell antibody infusions)
Cytokine storm (over-protective immune response that can actually be fatal)
Gastrointestinal haemorrhage (bleeding gastrointestinal tract)
Haematuria (presence of blood in urine)
Hyperkalaemia (damage to or disease of the kidney)
Hyperphosphataemia (electrolyte disturbance in which there is an abnormally elevated level of phosphate in the blood)
Hypocalcaemia (levels of calcium in blood serum are abnormally low)
Hypotension (abnormally low blood pressure)

What are the common drug interactions of Dotarem and Morphine, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

Bone pain
Seizure (abnormal excessive or synchronous neuronal activity in the brain)
Acute lymphocytic leukaemia recurrent (cancer in which the bone marrow makes too many lymphocytes-recurrent)
Blood creatinine increased
Blood lactic acid increased
Blood urea increased
Bone marrow failure
Bradycardia (abnormally slow heart action)
Cytokine release syndrome (immediate complication occurring with the use of anti-t cell antibody infusions)
Cytokine storm (over-protective immune response that can actually be fatal)

20-29:

n/a

30-39:

Nausea (feeling of having an urge to vomit)
Seizure (abnormal excessive or synchronous neuronal activity in the brain)
Vomiting

40-49:

n/a

50-59:

n/a

60+:

Bacteraemia (presence of bacteria in the blood)
Device failure
Nausea (feeling of having an urge to vomit)
Rash maculo-papular (red area on the skin that is covered with small confluent bumps)
Renal failure (kidney dysfunction)
Vomiting
Hypoglycaemia (deficiency of glucose in the bloodstream)
Hypotension (abnormally low blood pressure)
Small intestinal obstruction (blockage in small intestine)
Anaphylactic reaction (serious allergic reaction)

What are the existing conditions these people have? *

Constipation: 15 people, 62.50%
Nausea (feeling of having an urge to vomit): 12 people, 50.00%
Nausea And Vomiting: 12 people, 50.00%
Stress And Anxiety: 10 people, 41.67%
Pain In Extremity: 9 people, 37.50%
Acute Lymphocytic Leukemia (All) (cancer of the white blood cells characterized by excess lymphoblasts): 9 people, 37.50%
Birth Control: 9 people, 37.50%
Oral Herpes (viral infection of mouth): 9 people, 37.50%
Hypogammaglobulinaemia (an abnormally low concentration of gamma globulin in the blood and increased risk of infection): 8 people, 33.33%
Nervous System Disorder (a general class of medical conditions affecting the nervous system): 5 people, 20.83%

* Approximation only. Some reports may have incomplete information.

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