Doxazosin mesylate and Isoptin drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Doxazosin mesylate (doxazosin mesylate) and Isoptin (verapamil hydrochloride). Common drug interactions include overdose among females and atrial fibrillation among males.

The phase IV clinical study analyzes what interactions people have when they take Doxazosin mesylate and Isoptin. It is created by eHealthMe based on reports of 12 people who take the same drugs from the FDA, and is updated regularly.

What is Doxazosin mesylate?

Doxazosin mesylate has active ingredients of doxazosin mesylate. It is often used in high blood pressure. eHealthMe is studying from 11,975 Doxazosin mesylate users. Check the latest studies of Doxazosin mesylate.

What is Isoptin?

Isoptin has active ingredients of verapamil hydrochloride. It is often used in high blood pressure. eHealthMe is studying from 5,539 Isoptin users. Check the latest studies of Isoptin.



On Jul, 09, 2026

12 people who take Doxazosin mesylate and Isoptin together, and have interactions are studied.

Doxazosin mesylate and Isoptin drug interactions.

What are the common drug interactions of Doxazosin Mesylate and Isoptin, by gender? *:

female:

  1. Overdose
  2. Suicide attempt
  3. Alopecia (absence of hair from areas of the body)

male:

  1. Atrial fibrillation (fibrillation of the muscles of the atria of the heart)
  2. Malignant pleural effusion (a condition in which cancer causes an abnormal amount of fluid to collect between the thin layers of tissue lining of lung)
  3. Heart rate irregular
  4. Pneumonia
  5. Chest discomfort
  6. Dizziness
  7. Dyspnoea (difficult or laboured respiration)
  8. Hypocalcaemia (levels of calcium in blood serum are abnormally low)
  9. Hypokalaemia (low potassium)
  10. Inappropriate antidiuretic hormone secretion

What are the common drug interactions of Doxazosin Mesylate and Isoptin, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

  1. Overdose
  2. Suicide attempt

30-39:

n/a

40-49:

n/a

50-59:

  1. Vomiting
  2. Bronchostenosis (narrowing of a bronchial tube by scarring or other stricture)
  3. Erythema (redness of the skin)
  4. Flushing (the warm, red condition of human skin)
  5. Chest discomfort
  6. Dizziness
  7. Drug ineffective
  8. Hypocalcaemia (levels of calcium in blood serum are abnormally low)
  9. Nodal arrhythmia (an irregular heart beat originating from within the atrioventricular node)
  10. Overdose

60+:

  1. Atrial fibrillation (fibrillation of the muscles of the atria of the heart)
  2. Malignant pleural effusion (a condition in which cancer causes an abnormal amount of fluid to collect between the thin layers of tissue lining of lung)
  3. Hypokalaemia (low potassium)
  4. Inappropriate antidiuretic hormone secretion
  5. Leukopenia (less number of white blood cells in blood)
  6. Lung infiltration (a substance that normally includes fluid, inflammatory exudates or cells that fill a region of lung)
  7. Malaise (a feeling of general discomfort or uneasiness)
  8. Neutropenia (an abnormally low number of neutrophils)
  9. Pleural effusion (water on the lungs)
  10. Post procedural complication

What are the existing conditions these people have? *

  1. Suicide Attempt: 2 people, 16.67%
  2. Essential Hypertension (primary hypertension): 2 people, 16.67%
  3. Asthma: 2 people, 16.67%
  4. Lung Cancer - Non-Small Cell (lung cancer): 1 person, 8.33%
  5. Heart Disease: 1 person, 8.33%
  6. Diabetes: 1 person, 8.33%

* Approximation only. Some reports may have incomplete information.

Do you take Doxazosin mesylate and Isoptin?

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Doxazosin mesylate and Isoptin:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Doxazosin mesylate:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Isoptin:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Doxazosin mesylate and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Isoptin and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

How the study uses the data?

The study uses data from the FDA. It is based on doxazosin mesylate and verapamil hydrochloride (the active ingredients of Doxazosin mesylate and Isoptin, respectively), and Doxazosin mesylate and Isoptin (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

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