Doxil and Solu-medrol drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Doxil (doxorubicin hydrochloride) and Solu-medrol (methylprednisolone sodium succinate). Common drug interactions include disseminated intravascular coagulation among females and pyrexia among males.

The phase IV clinical study analyzes what interactions people have when they take Doxil and Solu-medrol. It is created by eHealthMe based on reports of 57 people who take the same drugs from the FDA, and is updated regularly.

What is Doxil?

Doxil has active ingredients of doxorubicin hydrochloride. It is often used in ovarian cancer. eHealthMe is studying from 10,479 Doxil users. Check the latest studies of Doxil.

What is Solu-medrol?

Solu-medrol has active ingredients of methylprednisolone sodium succinate. It is often used in multiple sclerosis. eHealthMe is studying from 39,410 Solu-medrol users. Check the latest studies of Solu-medrol.

On Aug, 11, 2026

57 people who take Doxil and Solu-medrol together, and have interactions are studied.

Doxil and Solu-medrol drug interactions.

What are the common drug interactions of Doxil and Solu-Medrol, by gender? *:

female:

Disseminated intravascular coagulation (systemic activation of blood coagulation)
Interstitial lung disease
Restlessness (not able to rest)
Pyrexia (fever)
Fatigue (feeling of tiredness)
Gastrointestinal infection (infection of stomach and intestine)
Disease progression
Dyspnoea (difficult or laboured respiration)
Septic shock (shock due to blood infection)
Death

male:

Pyrexia (fever)
Anxiety
Deep vein thrombosis (blood clot in a major vein that usually develops in the legs and/or pelvis)
Gastrooesophageal reflux disease (stomach contents (food or liquid) leak backwards from the stomach into the oesophagus)
Abdominal pain
Arthritis (form of joint disorder that involves inflammation of one or more joints)
Bone disorder
Breast mass
Calculus ureteric (stone in ureter)
Cellulitis (infection under the skin)

What are the common drug interactions of Doxil and Solu-Medrol, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

Constipation
Death
Dehydration (dryness resulting from the removal of water)
Dyspnoea (difficult or laboured respiration)
Fatigue (feeling of tiredness)
Flank pain (a distressing sensation experienced around the lower back and the upper abdomen)
Nausea (feeling of having an urge to vomit)
Palmar-plantar erythrodysaesthesia syndrome (hand-foot syndrome)
Sinusitis (inflammation of sinus)
Anxiety

50-59:

Tricuspid valve incompetence (inefficient heart valve)
Weight decreased
Abdominal hernia
Adrenal insufficiency (a condition in which the adrenal glands do not produce adequate amounts of steroids)
Amnesia (deficit in memory caused by brain damage, disease, or psychological trauma)
Anxiety
Aortic valve incompetence
Arthralgia (joint pain)
Atelectasis (partial or complete collapse of the lung)
Benign prostatic hyperplasia (benign enlargement of the prostate)

60+:

Deep vein thrombosis (blood clot in a major vein that usually develops in the legs and/or pelvis)
Disseminated intravascular coagulation (systemic activation of blood coagulation)
Pancytopenia (medical condition in which there is a reduction in the number of red and white blood cells, as well as platelets)
Restlessness (not able to rest)
Pyrexia (fever)
Anaemia (lack of blood)
Injury
Thrombocytopenia (decrease of platelets in blood)
Anhedonia (inability to experience pleasure from activities usually found enjoyable)
Anxiety

What are the existing conditions these people have? *

Non-Hodgkin's Lymphoma (malignant (cancer) cells form in the lymph system): 11 people, 19.30%
High Blood Pressure: 10 people, 17.54%
Fungal Infection: 10 people, 17.54%
Multiple Myeloma (cancer of the plasma cells): 9 people, 15.79%
Fever: 9 people, 15.79%
Constipation: 8 people, 14.04%
Diabetes: 8 people, 14.04%
Disseminated Intravascular Coagulation (systemic activation of blood coagulation): 8 people, 14.04%
Thrombocytopenia (decrease of platelets in blood): 8 people, 14.04%
Interstitial Lung Disease: 8 people, 14.04%

* Approximation only. Some reports may have incomplete information.

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