Doxycycline hyclate and Requip drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Doxycycline hyclate (doxycycline hyclate) and Requip (ropinirole hydrochloride). Common drug interactions include neuropathy peripheral among females and chronic obstructive pulmonary disease among males.

The phase IV clinical study analyzes what interactions people have when they take Doxycycline hyclate and Requip. It is created by eHealthMe based on reports of 88 people who take the same drugs from the FDA, and is updated regularly.

What is Doxycycline hyclate?

Doxycycline hyclate has active ingredients of doxycycline hyclate. It is often used in acne. eHealthMe is studying from 17,884 Doxycycline hyclate users. Check the latest studies of Doxycycline hyclate.

What is Requip?

Requip has active ingredients of ropinirole hydrochloride. It is often used in restless leg syndrome. eHealthMe is studying from 22,950 Requip users. Check the latest studies of Requip.

On Jul, 19, 2026

88 people who take Doxycycline hyclate and Requip together, and have interactions are studied.

Doxycycline hyclate and Requip drug interactions.

What are the common drug interactions of Doxycycline Hyclate and Requip, by gender? *:

female:

Neuropathy peripheral (surface nerve damage)
Pneumonia
Back pain
Back disorder
Bronchitis (inflammation of the mucous membrane in the bronchial tubes)
Cough
Fatigue (feeling of tiredness)
Feeling jittery
Gastrooesophageal reflux disease (stomach contents (food or liquid) leak backwards from the stomach into the oesophagus)
Hospitalisation

male:

Chronic obstructive pulmonary disease (a progressive disease that makes it hard to breathe)
Death
Confusional state
Dermatitis contact (skin reaction (dermatitis) resulting from exposure to allergens)
Drug hypersensitivity
Extrapyramidal disorder (involuntary muscle spasms in the face and neck)
Hallucination (an experience involving the perception of something not present)
Hepatic enzyme increased
Hiccups (an involuntary spasm of the diaphragm and respiratory organs, with a sudden closure of the glottis and a sound like a cough)
Narcolepsy (brain's inability to regulate sleep-wake cycles normally)

What are the common drug interactions of Doxycycline Hyclate and Requip, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

Cerebrovascular accident (sudden death of some brain cells due to lack of oxygen when the blood flow to the brain is impaired by blockage or rupture)
Chronic kidney disease
Gastrooesophageal reflux disease (stomach contents (food or liquid) leak backwards from the stomach into the oesophagus)
Glomerulonephritis (a group of conditions that affect parts of the kidneys called glomeruli)
Renal disorder (kidney disease)
Renal vein thrombosis (blood clot in renal vein)
Schizophrenia (a mental disorder characterized by a breakdown of thought processes)
Somnolence (a state of near-sleep, a strong desire for sleep)
Tachycardia (a heart rate that exceeds the range of 100 beats/min)
Weight decreased

50-59:

Gastrooesophageal reflux disease (stomach contents (food or liquid) leak backwards from the stomach into the oesophagus)
Nausea (feeling of having an urge to vomit)
Pain
Vomiting
Abdominal pain
Abscess (pus)
Actinomyces test positive
Adverse event
Anaphylactic reaction (serious allergic reaction)
Appendicitis (inflammation of the appendix)

60+:

Renal failure (kidney dysfunction)
Chronic kidney disease
Fall
Fatigue (feeling of tiredness)
Headache (pain in head)
Nausea (feeling of having an urge to vomit)
Neck pain
Pain
Injection site erythema (redness at injection site)
Injection site oedema

What are the existing conditions these people have? *

Narcolepsy (brain's inability to regulate sleep-wake cycles normally): 35 people, 39.77%
Cataplexy (loss of muscle tone accompanied by full conscious awareness): 20 people, 22.73%
Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 15 people, 17.05%
Multiple Sclerosis (a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath): 13 people, 14.77%
Pain: 11 people, 12.50%
Infection: 9 people, 10.23%
Stress And Anxiety: 7 people, 7.95%
High Blood Pressure: 7 people, 7.95%
High Blood Cholesterol: 7 people, 7.95%
Drowsiness: 7 people, 7.95%

* Approximation only. Some reports may have incomplete information.

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