Doxycycline and Effient drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Doxycycline (doxycycline hyclate) and Effient (prasugrel hydrochloride). Common drug interactions include diabetes mellitus among females and chronic kidney disease among males.

The phase IV clinical study analyzes what interactions people have when they take Doxycycline and Effient. It is created by eHealthMe based on reports of 56 people who take the same drugs from the FDA, and is updated regularly.

What is Doxycycline?

Doxycycline has active ingredients of doxycycline hyclate. It is often used in acne. eHealthMe is studying from 60,866 Doxycycline users. Check the latest studies of Doxycycline.

What is Effient?

Effient has active ingredients of prasugrel hydrochloride. It is often used in stent. eHealthMe is studying from 9,482 Effient users. Check the latest studies of Effient.



On Jul, 05, 2026

56 people who take Doxycycline and Effient together, and have interactions are studied.

Doxycycline and Effient drug interactions.

What are the common drug interactions of Doxycycline and Effient, by gender? *:

female:

  1. Diabetes mellitus (diabetes, caused by a deficiency of the pancreatic hormone insulin)
  2. Disease progression
  3. Fibula fracture
  4. Gastrooesophageal reflux disease (stomach contents (food or liquid) leak backwards from the stomach into the oesophagus)
  5. Haemoptysis (blood-stained sputum from the bronchi, larynx, trachea, or lungs)
  6. Hepatic steatosis (fatty liver disease)
  7. Hypersensitivity
  8. Hypertension (high blood pressure)
  9. Malaise (a feeling of general discomfort or uneasiness)
  10. Oral pain

male:

  1. Chronic kidney disease
  2. Renal failure (kidney dysfunction)
  3. Ill-defined disorder
  4. Death
  5. Renal injury (kidney injury)
  6. Anhedonia (inability to experience pleasure from activities usually found enjoyable)
  7. Anxiety
  8. Blood creatinine increased
  9. Bone density decreased
  10. Depression

What are the common drug interactions of Doxycycline and Effient, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

  1. Chronic kidney disease
  2. Nephrogenic anaemia (anaemia due to kidney disease)
  3. Anhedonia (inability to experience pleasure from activities usually found enjoyable)
  4. Anxiety
  5. Blood creatinine increased
  6. Bone density decreased
  7. Depression
  8. Emotional distress
  9. Mental disorder (a psychological term for a mental or behavioural pattern or anomaly that causes distress or disability)
  10. Myocardial infarction (destruction of heart tissue resulting from obstruction of the blood supply to the heart muscle)

50-59:

  1. Chronic kidney disease
  2. Renal failure (kidney dysfunction)
  3. Hyperparathyroidism secondary (an abnormally high concentration of parathyroid hormone in the blood, resulting in weakening of the bones through loss of calcium-secondary)
  4. Nephrogenic anaemia (anaemia due to kidney disease)
  5. Gastrooesophageal reflux disease (stomach contents (food or liquid) leak backwards from the stomach into the oesophagus)
  6. Death
  7. Angina pectoris (chest pain due to ischemia of the heart muscle)
  8. Ankle fracture
  9. Blood triglycerides increased
  10. Bone density decreased

60+:

  1. Chronic kidney disease
  2. Renal failure (kidney dysfunction)
  3. Chest discomfort
  4. Coronary artery reocclusion (blockage after treatment of coronary artery)
  5. Febrile neutropenia (fever with reduced white blood cells)
  6. Gait disturbance
  7. Hypocalcaemia (levels of calcium in blood serum are abnormally low)
  8. Hypomagnesaemia (electrolyte disturbance in which there is an abnormally low level of magnesium in the blood)
  9. Hyponatraemia (abnormally low level of sodium in the blood; associated with dehydration)
  10. Insomnia (sleeplessness)

What are the existing conditions these people have? *

  1. High Blood Pressure: 17 people, 30.36%
  2. Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 17 people, 30.36%
  3. High Blood Cholesterol: 15 people, 26.79%
  4. Pain: 13 people, 23.21%
  5. Cardiac Disorder: 9 people, 16.07%
  6. Infection: 9 people, 16.07%
  7. Rheumatoid Arthritis (a chronic progressive disease causing inflammation in the joints): 8 people, 14.29%
  8. Asthma: 6 people, 10.71%
  9. Chest Pain: 6 people, 10.71%
  10. Depression: 6 people, 10.71%

* Approximation only. Some reports may have incomplete information.

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Doxycycline and Effient:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Doxycycline:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Effient:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Doxycycline and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Effient and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

How the study uses the data?

The study uses data from the FDA. It is based on doxycycline hyclate and prasugrel hydrochloride (the active ingredients of Doxycycline and Effient, respectively), and Doxycycline and Effient (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

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