Doxycycline and Indocin drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Doxycycline (doxycycline hyclate) and Indocin (indomethacin). Common drug interactions include crying among females and dizziness among males.

The phase IV clinical study analyzes what interactions people have when they take Doxycycline and Indocin. It is created by eHealthMe based on reports of 35 people who take the same drugs from the FDA, and is updated regularly.

What is Doxycycline?

Doxycycline has active ingredients of doxycycline hyclate. It is often used in acne. eHealthMe is studying from 60,868 Doxycycline users. Check the latest studies of Doxycycline.

What is Indocin?

Indocin has active ingredients of indomethacin. It is often used in gout. eHealthMe is studying from 4,559 Indocin users. Check the latest studies of Indocin.

On Aug, 04, 2026

35 people who take Doxycycline and Indocin together, and have interactions are studied.

Doxycycline and Indocin drug interactions.

What are the common drug interactions of Doxycycline and Indocin, by gender? *:

female:

Crying
Deep vein thrombosis (blood clot in a major vein that usually develops in the legs and/or pelvis)
Fasciitis (infection of muscle surrounding tissue)
Hot flush (sudden feelings of heat)
Injury
Intervertebral disc protrusion (spinal disc protrusion)
Tendonitis (a condition that causes pain and swelling of tendons)
Renal failure (kidney dysfunction)
Compulsive shopping
Fatigue (feeling of tiredness)

male:

Dizziness
Dyspnoea (difficult or laboured respiration)
Death
Deformity (disfigurement)
Loss of consciousness
Lung infiltration (a substance that normally includes fluid, inflammatory exudates or cells that fill a region of lung)
Malaise (a feeling of general discomfort or uneasiness)
Muscle spasms (muscle contraction)
Musculoskeletal pain (pain affects the bones, muscles, ligaments, tendons, and nerves)
Renal failure (kidney dysfunction)

What are the common drug interactions of Doxycycline and Indocin, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

Deep vein thrombosis (blood clot in a major vein that usually develops in the legs and/or pelvis)
Depression
Injury

20-29:

n/a

30-39:

Chronic kidney disease
Renal failure (kidney dysfunction)
Nephropathy (damage to or disease of a kidney)

40-49:

Chronic kidney disease
Dizziness
Pain in extremity
Renal failure (kidney dysfunction)
Ankylosing spondylitis (type of arthritis affecting the spine)
Chronic fatigue syndrome (disorder that causes extreme fatigue)
Crying
Depression
Drug hypersensitivity
Fasciitis (infection of muscle surrounding tissue)

50-59:

Somnolence (a state of near-sleep, a strong desire for sleep)
Tongue oedema (swelling of tongue)
Dysphagia (a condition in which swallowing is difficult or painful)
Dyspnoea (difficult or laboured respiration)
Fatigue (feeling of tiredness)
Macular oedema (fluid and protein deposits collect on or under the macula of the eye (a yellow central area of the retina) and causes it to thicken)

60+:

Osteoarthritis (a joint disease caused by cartilage loss in a joint)
Anxiety
Lung infiltration (a substance that normally includes fluid, inflammatory exudates or cells that fill a region of lung)
Malaise (a feeling of general discomfort or uneasiness)
Muscle spasms (muscle contraction)
Musculoskeletal pain (pain affects the bones, muscles, ligaments, tendons, and nerves)
Spinal osteoarthritis (joint cartilage loss in spine)
Tricuspid valve incompetence (inefficient heart valve)
Ventricular hypertrophy (enlargement of ventricles (lower chambers) in the heart)
Anaemia (lack of blood)

What are the existing conditions these people have? *

Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 7 people, 20.00%
Multiple Myeloma (cancer of the plasma cells): 6 people, 17.14%
Pain: 4 people, 11.43%
High Blood Cholesterol: 4 people, 11.43%
Multiple Allergies (allergy to multiple agents): 4 people, 11.43%
Insomnia (sleeplessness): 3 people, 8.57%
Crohn's Disease (a condition that causes inflammation of the gastrointestinal tract): 3 people, 8.57%
Cardiac Failure Congestive: 3 people, 8.57%
Constipation: 2 people, 5.71%
Cough: 2 people, 5.71%

* Approximation only. Some reports may have incomplete information.

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