Doxycycline and Prometrium drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Doxycycline (doxycycline hyclate) and Prometrium (progesterone). Common drug interactions include pain among females.

The phase IV clinical study analyzes what interactions people have when they take Doxycycline and Prometrium. It is created by eHealthMe based on reports of 60 people who take the same drugs from the FDA, and is updated regularly.

What is Doxycycline?

Doxycycline has active ingredients of doxycycline hyclate. It is often used in acne. eHealthMe is studying from 60,868 Doxycycline users. Check the latest studies of Doxycycline.

What is Prometrium?

Prometrium has active ingredients of progesterone. It is often used in menopause. eHealthMe is studying from 5,980 Prometrium users. Check the latest studies of Prometrium.

On Aug, 02, 2026

60 people who take Doxycycline and Prometrium together, and have interactions are studied.

Doxycycline and Prometrium drug interactions.

What are the common drug interactions of Doxycycline and Prometrium, by gender? *:

female:

Pain
Fall
Pruritus (severe itching of the skin)
Tooth fracture
Tooth loss
Abdominal pain
Abdominal pain upper
Actinomycosis (infection that causes sores, or abscesses)
Anaemia (lack of blood)
Angiopathy (generic term for a disease of the blood vessels)

male:

n/a

What are the common drug interactions of Doxycycline and Prometrium, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

Hydrocephalus (water on the brain)

40-49:

Fatigue (feeling of tiredness)
Back pain
Fall
Oedema peripheral (superficial swelling)
Pain
Somnolence (a state of near-sleep, a strong desire for sleep)
Abdominal pain
Abdominal pain upper
Actinomycosis (infection that causes sores, or abscesses)
Amnesia (deficit in memory caused by brain damage, disease, or psychological trauma)

50-59:

Spinal osteoarthritis (joint cartilage loss in spine)
Bone density decreased
Lymphocyte count decreased
Diuretic therapy
Stem cell transplant
Tooth extraction
Viith nerve paralysis
Osteonecrosis of jaw (death of bone of jaw)
Exostosis (formation of new bone on the surface of a bone)
Skin fibrosis (fibrous tissue formation on skin)

60+:

Lymphadenitis (inflammation or enlargement of a lymph node)
Skin infection
Drug intolerance (drug sensitivity)
Ear infection
Eye pain
Fungal infection
Infusion site pruritus (severe itching at infusion site)
Injection site pain
Nausea (feeling of having an urge to vomit)
Panic reaction

What are the existing conditions these people have? *

High Blood Pressure: 22 people, 36.67%
Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 21 people, 35.00%
Multiple Myeloma (cancer of the plasma cells): 15 people, 25.00%
Fatigue (feeling of tiredness): 14 people, 23.33%
Immunodeficiency Common Variable: 9 people, 15.00%
Depression: 8 people, 13.33%
Insomnia (sleeplessness): 8 people, 13.33%
Urinary Tract Infection: 6 people, 10.00%
Urinary Incontinence (inability to control the flow of urine and involuntary urination): 6 people, 10.00%
Fibromyalgia (a long-term condition which causes pain all over the body): 6 people, 10.00%

* Approximation only. Some reports may have incomplete information.

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