Drisdol and Actigall drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Drisdol (ergocalciferol) and Actigall (ursodiol). Common drug interactions include iron deficiency anaemia among females and bile duct stone among males.

The phase IV clinical study analyzes what interactions people have when they take Drisdol and Actigall. It is created by eHealthMe based on reports of 16 people who take the same drugs from the FDA, and is updated regularly.

What is Drisdol?

Drisdol has active ingredients of ergocalciferol. It is often used in vitamin d. eHealthMe is studying from 1,740 Drisdol users. Check the latest studies of Drisdol.

What is Actigall?

Actigall has active ingredients of ursodiol. It is often used in gallstones. eHealthMe is studying from 2,162 Actigall users. Check the latest studies of Actigall.



On Jul, 13, 2026

16 people who take Drisdol and Actigall together, and have interactions are studied.

Drisdol and Actigall drug interactions.

What are the common drug interactions of Drisdol and Actigall, by gender? *:

female:

  1. Iron deficiency anaemia
  2. Portal hypertensive gastropathy (changes in the mucosa of the stomach in patients with portal hypertension;)
  3. Varices oesophageal (enlarged and swollen veins at the bottom of the oesophagus, near the stomach)
  4. Weight decreased
  5. Nodule (a growth of abnormal tissue)
  6. Pain
  7. Cytomegalovirus viraemia (cytomegalo virus in blood stream)
  8. Sinus tachycardia (a heart rhythm with elevated rate of impulses originating from the sinoatrial node)
  9. Venoocclusive liver disease (small veins in the liver are obstructed)
  10. Bilirubin conjugated increased

male:

  1. Bile duct stone
  2. Infective pulmonary exacerbation of cystic fibrosis (severe infective lung disease with production of abnormally thick mucus)
  3. Adenoviral upper respiratory infection (viral upper respiratory infection)
  4. Dysgeusia (disorder of the sense of taste)
  5. Erectile dysfunction
  6. Libido decreased (loss of interest in sex)
  7. Pseudomonas infection (pseudomonas infection is caused by a bacterium, pseudomonas aeruginosa)

What are the common drug interactions of Drisdol and Actigall, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

  1. Bilirubin conjugated increased
  2. Decreased appetite
  3. Eye disorder
  4. Hepatic mass
  5. Hepatocellular carcinoma (liver cancer)
  6. Ocular icterus (presence of jaundice seen in the sclera of the eye)

20-29:

  1. Bile duct stone
  2. Cytomegalovirus viraemia (cytomegalo virus in blood stream)
  3. Sinus tachycardia (a heart rhythm with elevated rate of impulses originating from the sinoatrial node)
  4. Infective pulmonary exacerbation of cystic fibrosis (severe infective lung disease with production of abnormally thick mucus)

30-39:

n/a

40-49:

n/a

50-59:

n/a

60+:

  1. Fatigue (feeling of tiredness)
  2. Haematochezia (passage of stools containing blood)
  3. Oesophageal mass
  4. Hepatic cirrhosis (chronic liver disease characterized by replacement of liver tissue by fibrosis, scar tissue)
  5. Iron deficiency anaemia
  6. Portal hypertensive gastropathy (changes in the mucosa of the stomach in patients with portal hypertension;)
  7. Varices oesophageal (enlarged and swollen veins at the bottom of the oesophagus, near the stomach)
  8. Weight decreased
  9. Venoocclusive liver disease (small veins in the liver are obstructed)
  10. Nodule (a growth of abnormal tissue)

What are the existing conditions these people have? *

  1. Pain: 5 people, 31.25%
  2. Cystic Fibrosis (disease of the secretary glands): 4 people, 25.00%
  3. Rickets (softening of bones): 3 people, 18.75%
  4. Graft Versus Host Disease (the donated bone marrow or stem cells view the recipient's body as foreign, and the donated cells/bone marrow attack the body): 3 people, 18.75%
  5. Acute Lymphocytic Leukemia (All) (cancer of the white blood cells characterized by excess lymphoblasts): 2 people, 12.50%
  6. Seasonal Allergy (allergic condition due to certain season): 2 people, 12.50%
  7. Cystic Fibrosis Lung (fibrosis with cyst in the lung): 2 people, 12.50%
  8. Hepatic Enzyme Increased: 2 people, 12.50%
  9. Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 2 people, 12.50%
  10. Dry Eyes (lack of adequate tears): 1 person, 6.25%

* Approximation only. Some reports may have incomplete information.

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Drisdol and Actigall:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Drisdol:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Actigall:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Drisdol and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Actigall and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Related publications that referenced our studies


How the study uses the data?

The study uses data from the FDA. It is based on ergocalciferol and ursodiol (the active ingredients of Drisdol and Actigall, respectively), and Drisdol and Actigall (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



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