Dronabinol and Megace drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Dronabinol (dronabinol) and Megace (megestrol acetate). Common drug interactions include pain among females and renal failure among males.

The phase IV clinical study analyzes what interactions people have when they take Dronabinol and Megace. It is created by eHealthMe based on reports of 40 people who take the same drugs from the FDA, and is updated regularly.

What is Dronabinol?

Dronabinol has active ingredients of dronabinol. eHealthMe is studying from 5,453 Dronabinol users. Check the latest studies of Dronabinol.

What is Megace?

Megace has active ingredients of megestrol acetate. It is often used in weight loss. eHealthMe is studying from 10,095 Megace users. Check the latest studies of Megace.



On Jul, 15, 2026

40 people who take Dronabinol and Megace together, and have interactions are studied.

Dronabinol and Megace drug interactions.

What are the common drug interactions of Dronabinol and Megace, by gender? *:

female:

  1. Pain
  2. Pneumonia
  3. Pruritus (severe itching of the skin)
  4. Arthralgia (joint pain)
  5. Cardiac disorder
  6. Chronic kidney disease
  7. Diarrhoea
  8. Exercise tolerance decreased
  9. Insomnia (sleeplessness)
  10. Lipodystrophy acquired (a regional loss of subcutaneous adipose tissue which usually starts in the face, extends downward acquired)

male:

  1. Renal failure (kidney dysfunction)
  2. Emotional distress
  3. Metabolic acidosis (body produces too much acid, or when the kidneys are not removing enough acid from the body)
  4. Respiratory failure (inadequate gas exchange by the respiratory system)
  5. Septic shock (shock due to blood infection)
  6. Anaemia (lack of blood)
  7. Cardiac arrest
  8. Osteopenia (a condition where bone mineral density is lower than normal)
  9. Renal tubular necrosis (death of kidney tubules)
  10. Ankle fracture

What are the common drug interactions of Dronabinol and Megace, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

  1. Emotional distress
  2. Fatigue (feeling of tiredness)
  3. Multiple fractures
  4. Pain
  5. Renal failure (kidney dysfunction)
  6. Amnesia (deficit in memory caused by brain damage, disease, or psychological trauma)
  7. Anaemia (lack of blood)
  8. Asthenia (weakness)
  9. Balance disorder
  10. Blood amylase increased

50-59:

  1. Renal failure (kidney dysfunction)
  2. Bone density decreased
  3. Emotional distress
  4. Pain
  5. Anhedonia (inability to experience pleasure from activities usually found enjoyable)
  6. Anxiety
  7. Multiple fractures
  8. Hypokalaemia (low potassium)
  9. Encephalopathy (functioning of the brain is affected by some agent or condition)
  10. Metabolic acidosis (body produces too much acid, or when the kidneys are not removing enough acid from the body)

60+:

  1. Dehydration (dryness resulting from the removal of water)
  2. Dyspnoea (difficult or laboured respiration)
  3. Pruritus (severe itching of the skin)
  4. Tremor (trembling or shaking movements in one or more parts of your body)
  5. Abdominal distension
  6. Aspartate aminotransferase increased
  7. Asthenia (weakness)
  8. Blood alkaline phosphatase increased
  9. Blood bilirubin increased
  10. Blood glucose increased

What are the existing conditions these people have? *

  1. Hiv Infection: 11 people, 27.50%
  2. Pain: 8 people, 20.00%
  3. Multiple Myeloma (cancer of the plasma cells): 8 people, 20.00%
  4. Nausea (feeling of having an urge to vomit): 7 people, 17.50%
  5. Constipation: 6 people, 15.00%
  6. Stress And Anxiety: 5 people, 12.50%
  7. Anaemia (lack of blood): 4 people, 10.00%
  8. Asthma: 4 people, 10.00%
  9. Diarrhea: 4 people, 10.00%
  10. Nausea And Vomiting: 4 people, 10.00%

* Approximation only. Some reports may have incomplete information.

Do you take Dronabinol and Megace?

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Dronabinol and Megace:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Dronabinol:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Megace:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Dronabinol and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Megace and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

How the study uses the data?

The study uses data from the FDA. It is based on dronabinol and megestrol acetate (the active ingredients of Dronabinol and Megace, respectively), and Dronabinol and Megace (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

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