Dulcolax and Ditropan drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Dulcolax (bisacodyl) and Ditropan (oxybutynin chloride). Common drug interactions include headache among females and fall among males.

The phase IV clinical study analyzes what interactions people have when they take Dulcolax and Ditropan. It is created by eHealthMe based on reports of 97 people who take the same drugs from the FDA, and is updated regularly.

What is Dulcolax?

Dulcolax has active ingredients of bisacodyl. It is often used in constipation. eHealthMe is studying from 12,897 Dulcolax users. Check the latest studies of Dulcolax.

What is Ditropan?

Ditropan has active ingredients of oxybutynin chloride. It is often used in urge incontinence. eHealthMe is studying from 11,799 Ditropan users. Check the latest studies of Ditropan.



On Jul, 19, 2026

97 people who take Dulcolax and Ditropan together, and have interactions are studied.

Dulcolax and Ditropan drug interactions.

What are the common drug interactions of Dulcolax and Ditropan, by gender? *:

female:

  1. Headache (pain in head)
  2. Pain
  3. Pyrexia (fever)
  4. Radiculopathy (a set of conditions in which one or more nerves is affected and does not work properly)
  5. Weight decreased
  6. Chronic sinusitis (long lasting inflammation of the paranasal sinuses)
  7. Colitis ulcerative (inflammation of colon with ulcer)
  8. Dyspepsia (indigestion)
  9. Female genital tract fistula (passage in genital tract of female)
  10. Frequent bowel movements

male:

  1. Fall
  2. Sepsis (a severe blood infection that can lead to organ failure and death)
  3. Blood pressure decreased
  4. Cough
  5. Dysgeusia (disorder of the sense of taste)
  6. Haemothorax (collection of blood in the pleural space (the space between the lungs and the walls of the chest))
  7. Intestinal ischaemia (decreased supply of oxygenated blood to the intestines)
  8. Malaise (a feeling of general discomfort or uneasiness)
  9. Multiple injuries
  10. Presyncope

What are the common drug interactions of Dulcolax and Ditropan, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

  1. Nephrolithiasis (calculi in the kidneys)

20-29:

  1. Drug effect decreased
  2. Gastrointestinal motility disorder (abnormal intestinal contractions)

30-39:

  1. Dysphagia (a condition in which swallowing is difficult or painful)
  2. Erythema (redness of the skin)
  3. Femur fracture
  4. Hyperaesthesia
  5. Pain
  6. Pruritus (severe itching of the skin)

40-49:

  1. Device related infection
  2. Implant site infection
  3. Sepsis (a severe blood infection that can lead to organ failure and death)
  4. Asthenia (weakness)
  5. Cellulitis (infection under the skin)
  6. Central nervous system lesion (an abnormality in tissue of brain or spinal cord)
  7. Chronic kidney disease
  8. Confusional state
  9. Dizziness
  10. Enuresis (repeated inability to control urination)

50-59:

  1. Asthenia (weakness)
  2. Atelectasis (partial or complete collapse of the lung)
  3. Bladder dilatation
  4. Escherichia urinary tract infection (urinary tract infection by escherichia coli)
  5. Gait disturbance
  6. Generalised oedema (swelling all over the body)
  7. Hyperparathyroidism secondary (an abnormally high concentration of parathyroid hormone in the blood, resulting in weakening of the bones through loss of calcium-secondary)
  8. Hyponatraemia (abnormally low level of sodium in the blood; associated with dehydration)
  9. Memory impairment
  10. Meningitis (inflammation of the protective membranes covering the brain and spinal cord, known collectively as the meninges)

60+:

  1. Anaemia (lack of blood)
  2. Abdominal pain
  3. Colitis ulcerative (inflammation of colon with ulcer)
  4. Drug ineffective
  5. Erythema (redness of the skin)
  6. Female genital tract fistula (passage in genital tract of female)
  7. Frequent bowel movements
  8. Haematochezia (passage of stools containing blood)
  9. Headache (pain in head)
  10. Macular degeneration (painless eye condition that leads to the gradual loss of central vision)

What are the existing conditions these people have? *

  1. Multiple Sclerosis (a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath): 19 people, 19.59%
  2. Allergies: 16 people, 16.49%
  3. Crohn's Disease (a condition that causes inflammation of the gastrointestinal tract): 16 people, 16.49%
  4. High Blood Pressure: 14 people, 14.43%
  5. Pain: 14 people, 14.43%
  6. Colitis (inflammation of colon): 12 people, 12.37%
  7. Fever: 10 people, 10.31%
  8. Seizures (abnormal excessive or synchronous neuronal activity in the brain): 10 people, 10.31%
  9. Ulcerative Colitis (inflammatory bowel disease (ibd). it causes swelling, ulcerations, and loss of function of the large intestine): 10 people, 10.31%
  10. High Blood Cholesterol: 8 people, 8.25%

* Approximation only. Some reports may have incomplete information.

Do you take Dulcolax and Ditropan?

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Dulcolax and Ditropan:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Dulcolax:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Ditropan:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Dulcolax and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Ditropan and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

How the study uses the data?

The study uses data from the FDA. It is based on bisacodyl and oxybutynin chloride (the active ingredients of Dulcolax and Ditropan, respectively), and Dulcolax and Ditropan (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

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