Duoneb and Pacerone drug interactions - a phase IV clinical study of FDA data
Summary:
Drug interactions are reported among people who take Duoneb (albuterol sulfate; ipratropium bromide) and Pacerone (amiodarone hydrochloride). Common drug interactions include anhedonia among females and dyspnoea among males.
The phase IV clinical study analyzes what interactions people have when they take Duoneb and Pacerone. It is created by eHealthMe based on reports of 35 people who take the same drugs from the FDA, and is updated regularly.
What is Duoneb?
Duoneb has active ingredients of albuterol sulfate; ipratropium bromide. It is often used in chronic obstructive pulmonary disease. eHealthMe is studying from 8,093 Duoneb users. Check the latest studies of Duoneb.
What is Pacerone?
Pacerone has active ingredients of amiodarone hydrochloride. It is often used in atrial fibrillation/flutter. eHealthMe is studying from 2,814 Pacerone users. Check the latest studies of Pacerone.
35 people who take Duoneb and Pacerone together, and have interactions are studied.

What are the common drug interactions of Duoneb and Pacerone, by gender? *:
female:
- Anhedonia (inability to experience pleasure from activities usually found enjoyable)
- Arrhythmia supraventricular (irregular heartbeat supraventricular origin)
- Arthralgia (joint pain)
- Asthenia (weakness)
- Atrioventricular block complete (heart block complete)
- Blepharitis (chronic inflammation of the eyelid)
- Bronchitis (inflammation of the mucous membrane in the bronchial tubes)
- Cardiac arrest
- Cardioversion
- Carotid artery disease
male:
- Dyspnoea (difficult or laboured respiration)
- Fatigue (feeling of tiredness)
- Anaemia (lack of blood)
- Blood disorder
- Bronchitis (inflammation of the mucous membrane in the bronchial tubes)
- Cardiac failure congestive
- Dry mouth
- Fluid overload (too much fluid in the blood)
- Gait disturbance
- Haematochezia (passage of stools containing blood)
What are the common drug interactions of Duoneb and Pacerone, by age (0-1 to 60+)? *:
0-1:
n/a
2-9:
n/a
10-19:
n/a
20-29:
n/a
30-39:
n/a
40-49:
n/a
50-59:
- Arteriosclerosis (thickening and hardening of arteries)
- Arthralgia (joint pain)
- Blood pressure decreased
- Bronchitis (inflammation of the mucous membrane in the bronchial tubes)
- Cardiac failure congestive
- Cardiomyopathy (weakening of the heart muscle)
- Cytomegalovirus infection
- Depression
- Hypertension (high blood pressure)
- Malaise (a feeling of general discomfort or uneasiness)
60+:
- Hypotension (abnormally low blood pressure)
- Fatigue (feeling of tiredness)
- Bronchitis (inflammation of the mucous membrane in the bronchial tubes)
- Constipation
- Hyponatraemia (abnormally low level of sodium in the blood; associated with dehydration)
- Nausea (feeling of having an urge to vomit)
- Palpitations (feelings or sensations that your heart is pounding or racing)
- Pyrexia (fever)
- Rectal haemorrhage (bleeding from anus)
- Renal failure (kidney dysfunction)
What are the existing conditions these people have? *
- Pain: 8 people, 22.86%
- Nausea (feeling of having an urge to vomit): 6 people, 17.14%
- Dyspnea (difficult or laboured breathing): 6 people, 17.14%
- Stress And Anxiety: 4 people, 11.43%
- Rhinitis (a medical term for irritation and inflammation of the mucous membrane inside the nose): 3 people, 8.57%
- Primary Pulmonary Hypertension (primary high blood pressure that affects the arteries in the lungs and the right side of your heart): 3 people, 8.57%
- Oesophageal Carcinoma (cancer tumour of oesophagus): 3 people, 8.57%
- Diabetes: 3 people, 8.57%
- Constipation: 3 people, 8.57%
- Pneumonia: 2 people, 5.71%
* Approximation only. Some reports may have incomplete information.
Do you take Duoneb and Pacerone?
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Related studies:
Effectiveness of, side effects of, and alternative drugs to the 2 drugs:
Browse all drug interactions of Duoneb and Pacerone:
a b c d e f g h i j k l m n o p q r s t u v w x y zSub-studies by gender and age:
Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Browse all side effects of Duoneb:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all side effects of Pacerone:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Duoneb and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Pacerone and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zRelated publications that referenced our studies
- Tesic D, Kostic M, Paunovic D, Jankovic SM, "Analysis of the cost–effectiveness of dronedarone versus amiodarone, propafenone, and sotalol in patients with atrial fibrillation: results for Serbia", Kardiologia Polska (Polish Heart Journal), 2016 Jan .
- Kim DJ, Lee SC, Park GS, Kim GJ, Hwang WT, Lee CS, Lee MH, Hahn DH, Koh HC, "Amiodarone Induced Multiorgan Toxicity in a Patient of Hypertrophic Cardiomyopathy With Atrial Fibrillation", Journal of the Korean Geriatrics Society, 2013 Dec .
- Tesic D, Kostic M, Paunovic D, Jankovic SM, "Analysis of the cost–effectiveness of dronedarone versus amiodarone, propafenone, and sotalol in patients with atrial fibrillation: results for Serbia", Kardiologia Polska (Polish Heart Journal), 2016 Jan .
- Kim DJ, Lee SC, Park GS, Kim GJ, Hwang WT, Lee CS, Lee MH, Hahn DH, Koh HC, "Amiodarone Induced Multiorgan Toxicity in a Patient of Hypertrophic Cardiomyopathy With Atrial Fibrillation", Journal of the Korean Geriatrics Society, 2013 Dec .
How the study uses the data?
The study uses data from the FDA. It is based on albuterol sulfate; ipratropium bromide and amiodarone hydrochloride (the active ingredients of Duoneb and Pacerone, respectively), and Duoneb and Pacerone (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.
How to use the study?
DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.
Who is eHealthMe?
With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.
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