Isentress and Bone disorder - a phase IV clinical study of FDA data

Summary:

Bone disorder is reported as a side effect among people who take Isentress (raltegravir potassium), especially for people who are male, 50-59 old, have been taking the drug for 2 - 5 years also take Truvada, and have Nausea.

The phase IV clinical study analyzes which people have Bone disorder when taking Isentress. It is created by eHealthMe based on reports of 16,310 people who have side effects when taking Isentress from the FDA, and is updated regularly.

What is Isentress?

Isentress has active ingredients of raltegravir potassium. It is often used in hiv infection. eHealthMe is studying from 16,529 Isentress users. Check the latest studies of Isentress.

What is Bone disorder?

Bone disorder is found to be associated with 1,493 drugs and 1,308 conditions by eHealthMe. Check the latest studies of Bone disorder.

On Jul, 18, 2026

16,310 people reported to have side effects when taking Isentress.
Among them, 26 people (0.16%) have Bone disorder.

Among these 26 people:

How long have people been on Isentress when they have Bone disorder? *

What is the gender of people who have Bone disorder when taking Isentress? *

female: 19.23 %
male: 80.77 %

What is the age of people who have Bone disorder when taking Isentress? *

What are other drugs people take besides Isentress? *

What are other side effects people have besides Bone disorder? *

Emotional Distress: 22 people, 84.62%
Pain: 22 people, 84.62%
Anhedonia (inability to experience pleasure from activities usually found enjoyable): 19 people, 73.08%
Stress And Anxiety: 19 people, 73.08%
Bone Density Decreased: 10 people, 38.46%
Osteoporosis (bones weak and more likely to break): 8 people, 30.77%
Osteopenia (a condition where bone mineral density is lower than normal): 6 people, 23.08%
Depression: 6 people, 23.08%
Fatigue (feeling of tiredness): 6 people, 23.08%
Aseptic Necrosis (the death of bone tissue due to a lack of blood supply): 6 people, 23.08%

What are the existing conditions these people have? *

High Blood Pressure: 2 people, 7.69%
High Blood Cholesterol: 2 people, 7.69%
Nausea (feeling of having an urge to vomit): 2 people, 7.69%
Androgen Deficiency: 1 person, 3.85%
Atrial Fibrillation/flutter (atrial fibrillation and flutter are abnormal heart rhythms in which the atria, or upper chambers of the heart, are out of sync with the ventricles): 1 person, 3.85%
Bone Pain: 1 person, 3.85%
Depression: 1 person, 3.85%
Diabetes: 1 person, 3.85%
Face And Mouth X-Ray Abnormal: 1 person, 3.85%
Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 1 person, 3.85%

* Approximation only. Some reports may have incomplete information.

Do you take Isentress and have Bone disorder?

- Check whether Bone disorder is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Isentress:

Isentress (16,529 reports)

Bone disorder treatments and more:

Bone disorder (55,134 reports)

Browse all side effects of Isentress:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Bone disorder:

Bone disorder (1,493 drugs)

Browse all the conditions that are associated with Bone disorder:

Bone disorder (1,308 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on raltegravir potassium (the active ingredients of Isentress) and Isentress (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.