Amoxicillin and Peripheral ischaemia - a phase IV clinical study of FDA data

Summary:

Peripheral ischaemia is reported as a side effect among people who take Amoxicillin (amoxicillin), especially for people who are female, 60+ old, have been taking the drug for < 1 month also take Simvastatin, and have Colon cancer.

The phase IV clinical study analyzes which people have Peripheral ischaemia when taking Amoxicillin. It is created by eHealthMe based on reports of 95,831 people who have side effects when taking Amoxicillin from the FDA, and is updated regularly.

What is Amoxicillin?

Amoxicillin has active ingredients of amoxicillin. It is often used in infection. eHealthMe is studying from 99,235 Amoxicillin users. Check the latest studies of Amoxicillin.

What is Peripheral ischaemia?

Peripheral ischaemia (impaired circulation to an extremity) is found to be associated with 580 drugs and 645 conditions by eHealthMe. Check the latest studies of Peripheral ischaemia.

On Jul, 18, 2026

95,831 people reported to have side effects when taking Amoxicillin.
Among them, 52 people (0.05%) have Peripheral ischaemia.

Could Amoxicillin cause Peripheral ischaemia?

Among these 52 people:

How long have people been on Amoxicillin when they have Peripheral ischaemia? *

What is the gender of people who have Peripheral ischaemia when taking Amoxicillin? *

female: 63.27 %
male: 36.73 %

What is the age of people who have Peripheral ischaemia when taking Amoxicillin? *

What are other drugs people take besides Amoxicillin? *

What are other side effects people have besides Peripheral ischaemia? *

Urosepsis (secondary infection that occurs when a urinary tract infection spreads to the bloodstream): 19 people, 36.54%
Femoral Artery Embolism (obstruction in artery of femur bone): 19 people, 36.54%
Pulmonary Embolism (blockage of the main artery of the lung): 13 people, 25.00%
Dyspnea (difficult or laboured breathing): 6 people, 11.54%
Renal Impairment (severely reduced kidney function): 6 people, 11.54%
Abdominal Pain: 5 people, 9.62%
Oedema Peripheral (superficial swelling): 5 people, 9.62%
International Normalised Ratio Increased: 4 people, 7.69%
High Blood Pressure: 4 people, 7.69%
Sinus Tachycardia (a heart rhythm with elevated rate of impulses originating from the sinoatrial node): 4 people, 7.69%

What are the existing conditions these people have? *

Colon Cancer: 7 people, 13.46%
Atrial Fibrillation/flutter (atrial fibrillation and flutter are abnormal heart rhythms in which the atria, or upper chambers of the heart, are out of sync with the ventricles): 4 people, 7.69%
Stroke (sudden death of a portion of the brain cells due to a lack of oxygen): 4 people, 7.69%
Hepatitis B: 3 people, 5.77%
Upper Respiratory Tract Infection: 2 people, 3.85%
Type 2 Diabetes: 2 people, 3.85%
Blockage Of Leg Arteries: 2 people, 3.85%
Cardiac Disorder: 2 people, 3.85%
Chronic Myeloid Leukaemia (long lasting type of cancer that starts in the blood-forming cells of the bone marrow and invades the blood): 2 people, 3.85%
Dyslipidaemia (abnormal amount of lipids): 2 people, 3.85%

* Approximation only. Some reports may have incomplete information.

Do you take Amoxicillin and have Peripheral ischaemia?

- Check whether Peripheral ischaemia is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Amoxicillin:

Amoxicillin (99,235 reports)

Browse all side effects of Amoxicillin:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Peripheral ischaemia:

Peripheral ischaemia (580 drugs)

Browse all the conditions that are associated with Peripheral ischaemia:

Peripheral ischaemia (645 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on amoxicillin (the active ingredients of Amoxicillin) and Amoxicillin (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.