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Duopa and Paxil drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Duopa (carbidopa; levodopa) and Paxil (paroxetine hydrochloride). Common drug interactions include fall among females and fall among males.

The phase IV clinical study analyzes what interactions people have when they take Duopa and Paxil. It is created by eHealthMe based on reports of 43 people who take the same drugs from the FDA, and is updated regularly.

What is Duopa?

Duopa has active ingredients of carbidopa; levodopa. eHealthMe is studying from 8,208 Duopa users. Check the latest studies of Duopa.

What is Paxil?

Paxil has active ingredients of paroxetine hydrochloride. It is often used in depression. eHealthMe is studying from 92,546 Paxil users. Check the latest studies of Paxil.

On Jul, 15, 2026

43 people who take Duopa and Paxil together, and have interactions are studied.

Duopa and Paxil drug interactions.

What are the common drug interactions of Duopa and Paxil, by gender? *:

female:

  1. Fall
  2. Urinary tract infection
  3. Angiopathy (generic term for a disease of the blood vessels)
  4. Death
  5. Infection
  6. Insomnia (sleeplessness)
  7. Upper limb fracture
  8. Abdominal pain
  9. Asthenia (weakness)
  10. Device dislocation

male:

  1. Fall
  2. Device dislocation
  3. Drug ineffective
  4. Hip fracture
  5. Parkinson's disease
  6. Pneumonia
  7. Agitation (state of anxiety or nervous excitement)
  8. Asthenia (weakness)
  9. Device occlusion
  10. Dysphagia (a condition in which swallowing is difficult or painful)

What are the common drug interactions of Duopa and Paxil, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

n/a

50-59:

  1. Death
  2. Abdominal pain
  3. Dyskinesia (abnormality or impairment of voluntary movement)
  4. Pneumoperitoneum (air or gas in the abdominal (peritoneal) cavity)

60+:

  1. Fall
  2. Device dislocation
  3. Femur fracture
  4. Hip fracture
  5. Hypotension (abnormally low blood pressure)
  6. Parkinson's disease
  7. Rehabilitation therapy
  8. Agitation (state of anxiety or nervous excitement)
  9. Device occlusion
  10. Dysphagia (a condition in which swallowing is difficult or painful)

What are the existing conditions these people have? *

  1. Parkinson's Disease: 33 people, 76.74%
  2. Sleep Disorder: 4 people, 9.30%
  3. High Blood Pressure: 3 people, 6.98%
  4. Dry Eyes (lack of adequate tears): 3 people, 6.98%

* Approximation only. Some reports may have incomplete information.

Do you take Duopa and Paxil?

- Personalize this study to your gender, age, symptoms and drugs
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Duopa and Paxil:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Duopa:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Paxil:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Duopa and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Paxil and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Related publications that referenced our studies

How the study uses the data?

The study uses data from the FDA. It is based on carbidopa; levodopa and paroxetine hydrochloride (the active ingredients of Duopa and Paxil, respectively), and Duopa and Paxil (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.

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