Dupixent and Levaquin drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Dupixent (dupilumab) and Levaquin (levofloxacin). Common drug interactions include memory impairment among females and cellulitis among males.

The phase IV clinical study analyzes what interactions people have when they take Dupixent and Levaquin. It is created by eHealthMe based on reports of 93 people who take the same drugs from the FDA, and is updated regularly.

What is Dupixent?

Dupixent has active ingredients of dupilumab. eHealthMe is studying from 257,631 Dupixent users. Check the latest studies of Dupixent.

What is Levaquin?

Levaquin has active ingredients of levofloxacin. It is often used in sinusitis. eHealthMe is studying from 56,638 Levaquin users. Check the latest studies of Levaquin.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.



On Sep, 01, 2026

93 people who take Dupixent and Levaquin together, and have interactions are studied.

Dupixent and Levaquin drug interactions.

What are the common drug interactions of Dupixent and Levaquin, by gender? *:

female:

  1. Memory impairment
  2. Night sweats (sweating in night)
  3. Osteoporosis (bones weak and more likely to break)
  4. Palpitations (feelings or sensations that your heart is pounding or racing)
  5. Peripheral swelling
  6. Respiratory tract infection
  7. Seizure (abnormal excessive or synchronous neuronal activity in the brain)
  8. Spinal fracture (fracture in one of vertebrae)
  9. Asthma
  10. Arthralgia (joint pain)

male:

  1. Cellulitis (infection under the skin)
  2. Pruritus (severe itching of the skin)
  3. Fatigue (feeling of tiredness)
  4. Haemoptysis (blood-stained sputum from the bronchi, larynx, trachea, or lungs)
  5. Headache (pain in head)
  6. Hyperhidrosis (abnormally increased sweating)
  7. Injection site pain
  8. Klebsiella infection
  9. Limb injury
  10. Micturition urgency (urgency to pass the urine)

What are the common drug interactions of Dupixent and Levaquin, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

  1. Injection site pruritus (severe itching at injection site)

30-39:

  1. Asthma
  2. Headache (pain in head)
  3. Oral herpes (viral infection of mouth)
  4. Weight increased
  5. Ear infection
  6. Head injury
  7. Influenza
  8. Pharyngitis (inflammation of the pharynx, causing a sore throat)
  9. Pharyngitis streptococcal (inflammation of the pharynx caused by infection from. streptococcus)
  10. Rash

40-49:

  1. Dyspnoea (difficult or laboured respiration)
  2. Injection site pain
  3. Nausea (feeling of having an urge to vomit)
  4. Neurological symptom (symptoms of nervous system disease)
  5. Paranasal sinus discomfort
  6. Surgery
  7. Vomiting
  8. Cough
  9. Influenza
  10. Asthma

50-59:

  1. Arthralgia (joint pain)
  2. Asthma
  3. Retinal detachment (a disorder of the eye in which the retina peels away from its underlying layer of support tissue)
  4. Pain in extremity
  5. Back disorder
  6. Eye disorder
  7. Eye haemorrhage (bleeding in the eye)
  8. Injection site pain
  9. Vision blurred
  10. Visual impairment

60+:

  1. Rash
  2. Cellulitis (infection under the skin)
  3. Bronchitis (inflammation of the mucous membrane in the bronchial tubes)
  4. Cough
  5. Dehydration (dryness resulting from the removal of water)
  6. Discomfort
  7. Dry skin
  8. Fatigue (feeling of tiredness)
  9. Herpes zoster
  10. Infusion site extravasation (flow of (blood or lymph) from infusion site)

What are the existing conditions these people have? *

  1. Asthma: 44 people, 47.31%
  2. Dermatitis Atopic (inflammatory, chronically relapsing, non-contagious and pruritic skin disorder): 16 people, 17.20%
  3. Immunodeficiency Common Variable: 7 people, 7.53%

* Approximation only. Some reports may have incomplete information.

Do you take Dupixent and Levaquin?

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Dupixent and Levaquin:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Dupixent:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Levaquin:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Dupixent and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Levaquin and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Related publications that referenced our studies


How the study uses the data?

The study uses data from the FDA. It is based on dupilumab and levofloxacin (the active ingredients of Dupixent and Levaquin, respectively), and Dupixent and Levaquin (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



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