Durezol and Epipen drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Durezol (difluprednate) and Epipen (epinephrine). Common drug interactions include pain among females and constipation among males.

The phase IV clinical study analyzes what interactions people have when they take Durezol and Epipen. It is created by eHealthMe based on reports of 20 people who take the same drugs from the FDA, and is updated regularly.

What is Durezol?

Durezol has active ingredients of difluprednate. It is often used in uveitis. eHealthMe is studying from 3,441 Durezol users. Check the latest studies of Durezol.

What is Epipen?

Epipen has active ingredients of epinephrine. It is often used in anaphylaxis. eHealthMe is studying from 23,760 Epipen users. Check the latest studies of Epipen.

On Jul, 11, 2026

20 people who take Durezol and Epipen together, and have interactions are studied.

What are the common drug interactions of Durezol and Epipen, by gender? *:

female:

Pain
Dyspnoea (difficult or laboured respiration)
Eye disorder
Muscle fatigue (a condition in which muscles cannot exert their normal force)
Clavicle fracture
Eye pain
Eye swelling
Fall
Foot fracture
Gastrooesophageal reflux disease (stomach contents (food or liquid) leak backwards from the stomach into the oesophagus)

male:

Constipation
Headache (pain in head)
Diarrhoea
Nightmare (unpleasant dream)
Pain
Somnolence (a state of near-sleep, a strong desire for sleep)
Therapeutic response unexpected
Weight decreased
Weight increased
Nausea (feeling of having an urge to vomit)

What are the common drug interactions of Durezol and Epipen, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

Pain
Anhedonia (inability to experience pleasure from activities usually found enjoyable)
Anxiety
Bone pain
Bradycardia (abnormally slow heart action)
Cataract (clouding of the lens inside the eye)
Chronic kidney disease
Contusion (a type of hematoma of tissue in which capillaries)
Cough
Decreased activity

50-59:

Eye disorder
Muscle fatigue (a condition in which muscles cannot exert their normal force)
Clavicle fracture
Dyspnoea (difficult or laboured respiration)
Eye pain
Eye swelling
Fall
Foot fracture
Muscle rupture (tear in muscle)
Myasthenia gravis (a chronic condition that causes muscles to tire and weaken easily)

60+:

Headache (pain in head)
Nausea (feeling of having an urge to vomit)
Pain
Somnolence (a state of near-sleep, a strong desire for sleep)
Weight decreased
Vomiting
Abdominal pain
Chronic kidney disease
Decreased appetite
Gastrooesophageal reflux disease (stomach contents (food or liquid) leak backwards from the stomach into the oesophagus)

What are the existing conditions these people have? *

Asthma: 5 people, 25.00%
Narcolepsy (brain's inability to regulate sleep-wake cycles normally): 4 people, 20.00%
Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 3 people, 15.00%
Immunodeficiency Common Variable: 3 people, 15.00%
Rheumatoid Arthritis (a chronic progressive disease causing inflammation in the joints): 2 people, 10.00%
Gastrointestinal Motility Disorder (abnormal intestinal contractions): 2 people, 10.00%
Arthritis (form of joint disorder that involves inflammation of one or more joints): 2 people, 10.00%
Pain: 2 people, 10.00%
Sleep Disorder: 2 people, 10.00%
High Blood Cholesterol: 2 people, 10.00%

* Approximation only. Some reports may have incomplete information.

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