Echinacea and Clonazepam drug interactions - a phase IV clinical study of FDA data
Summary:
Drug interactions are reported among people who take Echinacea (echinacea) and Clonazepam (clonazepam). Common drug interactions include fluid retention among females and depression among males.
The phase IV clinical study analyzes what interactions people have when they take Echinacea and Clonazepam. It is created by eHealthMe based on reports of 85 people who take the same drugs from the FDA, and is updated regularly.
What is Echinacea?
Echinacea has active ingredients of echinacea. It is often used in immune response. eHealthMe is studying from 1,930 Echinacea users. Check the latest studies of Echinacea.
What is Clonazepam?
Clonazepam has active ingredients of clonazepam. It is often used in stress and anxiety. eHealthMe is studying from 146,270 Clonazepam users. Check the latest studies of Clonazepam.
85 people who take Echinacea and Clonazepam together, and have interactions are studied.

What are the common drug interactions of Echinacea and Clonazepam, by gender? *:
female:
- Fluid retention (an abnormal accumulation of fluid in the blood)
- Drug hypersensitivity
- Dysuria (painful or difficult urination)
- Muscular weakness (muscle weakness)
- Weight increased
- Pain
- Arthritis (form of joint disorder that involves inflammation of one or more joints)
- Food poisoning (poison in food)
- Infusion site oedema (swelling from excessive accumulation of watery fluid from infusion site)
- Peripheral swelling
male:
- Depression
- Weight increased
- Suicidal ideation
- Tinnitus (a ringing in the ears)
- Tremor (trembling or shaking movements in one or more parts of your body)
- Fatigue (feeling of tiredness)
- Drug ineffective
- Hypertension (high blood pressure)
- Weight decreased
- Cognitive disorder (mental health disorders affects learning, memory, perception, and problem solving)
What are the common drug interactions of Echinacea and Clonazepam, by age (0-1 to 60+)? *:
0-1:
n/a
2-9:
n/a
10-19:
n/a
20-29:
- Abdominal pain upper
- Biliary colic
- Cholecystitis chronic (long lasting infection of gallbladder)
- Cholelithiasis (the presence or formation of gallstones in the gallbladder or bile ducts)
- Nausea (feeling of having an urge to vomit)
- Vomiting
30-39:
- Depression
- Drug ineffective
- Endometriosis (appearance of endometrial tissue outside the uterus and causing pelvic pain)
- Uterine perforation (accidental puncture of the uterus)
40-49:
- Abdominal discomfort
- Blister (small pocket of fluid within the upper layers of the skin caused by forceful rubbing (friction), burning, freezing, chemical exposure)
- Confusional state
- Dermatitis contact (skin reaction (dermatitis) resulting from exposure to allergens)
- Diarrhoea
- Dizziness
- Drug hypersensitivity
- Drug intolerance (drug sensitivity)
- Dyspnoea (difficult or laboured respiration)
- Fall
50-59:
- Erection increased
- Increased appetite
- Nausea (feeling of having an urge to vomit)
- Suicidal ideation
- Tinnitus (a ringing in the ears)
- Weight increased
- Fatigue (feeling of tiredness)
- Drug ineffective
- Night sweats (sweating in night)
- Transient ischaemic attack (a transient episode of neurologic dysfunction caused by ischemia (loss of blood flow))
60+:
- Fatigue (feeling of tiredness)
- Fall
- Diabetes mellitus (diabetes, caused by a deficiency of the pancreatic hormone insulin)
- Drug ineffective
- Dyspnoea (difficult or laboured respiration)
- Fluid retention (an abnormal accumulation of fluid in the blood)
- Headache (pain in head)
- Impaired work ability
- Influenza like illness
- Malaise (a feeling of general discomfort or uneasiness)
What are the existing conditions these people have? *
- Sleep Disorder: 19 people, 22.35%
- Immunodeficiency Common Variable: 17 people, 20.00%
- Narcolepsy (brain's inability to regulate sleep-wake cycles normally): 11 people, 12.94%
- Multiple Sclerosis (a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath): 11 people, 12.94%
- Depression: 7 people, 8.24%
- Combined Immunodeficiency: 6 people, 7.06%
- Cataplexy (loss of muscle tone accompanied by full conscious awareness): 5 people, 5.88%
* Approximation only. Some reports may have incomplete information.
Do you take Echinacea and Clonazepam?
- Personalize this study to your gender, age, symptoms and drugs
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously
Related studies:
Effectiveness of, side effects of, and alternative drugs to the 2 drugs:
- Echinacea (1,930 reports)
- Clonazepam (146,270 reports)
Browse all drug interactions of Echinacea and Clonazepam:
a b c d e f g h i j k l m n o p q r s t u v w x y zSub-studies by gender and age:
Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Browse all side effects of Echinacea:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all side effects of Clonazepam:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Echinacea and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Clonazepam and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zRelated publications that referenced our studies
- McFarlane SI, "Torsades de Pointes induced by Methadone and Clonazepam Use", , 2015 Jan .
- Ashkar AG, Goldberg T, Maraj I, Masters A, McFarlane SI, "Torsades De Pointes Induced by Methadone and Clonazepam Use", International Journal of Medical and Pharmaceutical Case Reports, 2015 Jan .
- McFarlane, S. I. , "Torsades de Pointes induced by Methadone and Clonazepam Use", , 2014 Jan .
- McFarlane SI, "Torsades de Pointes induced by Methadone and Clonazepam Use", , 2015 Jan .
- Ashkar AG, Goldberg T, Maraj I, Masters A, McFarlane SI, "Torsades De Pointes Induced by Methadone and Clonazepam Use", International Journal of Medical and Pharmaceutical Case Reports, 2015 Jan .
- McFarlane, S. I. , "Torsades de Pointes induced by Methadone and Clonazepam Use", , 2014 Jan .
How the study uses the data?
The study uses data from the FDA. It is based on echinacea and clonazepam (the active ingredients of Echinacea and Clonazepam, respectively), and Echinacea and Clonazepam (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.
How to use the study?
DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.
Who is eHealthMe?
With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.
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