Econazole nitrate and Zide drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Econazole nitrate (econazole nitrate) and Zide (hydrochlorothiazide). Common drug interactions include decreased appetite among females and chronic kidney disease among males.

The phase IV clinical study analyzes what interactions people have when they take Econazole nitrate and Zide. It is created by eHealthMe based on reports of 76 people who take the same drugs from the FDA, and is updated regularly.

What is Econazole nitrate?

Econazole nitrate has active ingredients of econazole nitrate. It is often used in athlete's foot. eHealthMe is studying from 1,264 Econazole nitrate users. Check the latest studies of Econazole nitrate.

What is Zide?

Zide has active ingredients of hydrochlorothiazide. It is often used in high blood pressure. eHealthMe is studying from 183,246 Zide users. Check the latest studies of Zide.

On Jul, 12, 2026

76 people who take Econazole nitrate and Zide together, and have interactions are studied.

Econazole nitrate and Zide drug interactions.

What are the common drug interactions of Econazole Nitrate and Zide, by gender? *:

female:

Decreased appetite
Deep vein thrombosis (blood clot in a major vein that usually develops in the legs and/or pelvis)
Deformity (disfigurement)
Dementia (madness)
Fall
Gastrointestinal haemorrhage (bleeding gastrointestinal tract)
Haemoptysis (blood-stained sputum from the bronchi, larynx, trachea, or lungs)
Infection
Joint injury
Metastases to central nervous system (cancer spreads to central nervous system)

male:

Chronic kidney disease
Pain in extremity
Presyncope
Rash
Thrombocytopenia (decrease of platelets in blood)
Vasculitis (inflammation of a blood vessel or blood vessels)
Abdominal abscess (collection of pus in abdomen)
Abdominal pain
Abdominal pain upper
Abnormal loss of weight

What are the common drug interactions of Econazole Nitrate and Zide, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

Atrial tachycardia (rhythm disturbance that arises in the atria)
Chronic kidney disease
Dizziness
Dry skin
Dyspnoea (difficult or laboured respiration)
Eyelid skin dryness
Headache (pain in head)
Injection site pruritus (severe itching at injection site)
Kaposi's sarcoma (a tumour caused by human herpes virus)
Lacrimation increased

50-59:

Temporomandibular joint syndrome (pain at the temporomandibular joint due to various causes of increased muscle tension and spasm. it is believed that syndrome is a physical manifestation of psychological stress)
Abdominal pain
Abnormal loss of weight
Acarodermatitis (skin inflammation caused by mites (acarids))
Adverse drug reaction
Angioedema (rapid swelling of the dermis)
Arteriosclerosis (thickening and hardening of arteries)
Asthenia (weakness)
Benign prostatic hyperplasia (benign enlargement of the prostate)
Blood triglycerides increased

60+:

Anaemia (lack of blood)
Depression
Breast cancer metastatic
Carotid bruit (sound heard over the carotid artery area during auscultation)
Chronic obstructive pulmonary disease (a progressive disease that makes it hard to breathe)
Chronic sinusitis (long lasting inflammation of the paranasal sinuses)
Decreased appetite
Deep vein thrombosis (blood clot in a major vein that usually develops in the legs and/or pelvis)
Deformity (disfigurement)
Dementia (madness)

What are the existing conditions these people have? *

Hypercalcaemia Of Malignancy (elevated calcium (ca+) level in the blood with cancer): 15 people, 19.74%
Asthma: 13 people, 17.11%
Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 13 people, 17.11%
High Blood Cholesterol: 12 people, 15.79%
Pain: 11 people, 14.47%
Cardiac Disorder: 8 people, 10.53%
Insomnia (sleeplessness): 8 people, 10.53%
Depression: 7 people, 9.21%
Stress And Anxiety: 7 people, 9.21%
Rashes (redness): 7 people, 9.21%

* Approximation only. Some reports may have incomplete information.

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