Effexor and Estazolam drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Effexor (venlafaxine hydrochloride) and Estazolam (estazolam). Common drug interactions include hyperglycaemia among females and drug exposure during pregnancy among males.

The phase IV clinical study analyzes what interactions people have when they take Effexor and Estazolam. It is created by eHealthMe based on reports of 42 people who take the same drugs from the FDA, and is updated regularly.

What is Effexor?

Effexor has active ingredients of venlafaxine hydrochloride. It is often used in depression. eHealthMe is studying from 99,493 Effexor users. Check the latest studies of Effexor.

What is Estazolam?

Estazolam has active ingredients of estazolam. It is often used in insomnia. eHealthMe is studying from 2,758 Estazolam users. Check the latest studies of Estazolam.

On Jul, 17, 2026

42 people who take Effexor and Estazolam together, and have interactions are studied.

Effexor and Estazolam drug interactions.

What are the common drug interactions of Effexor and Estazolam, by gender? *:

female:

Hyperglycaemia (high blood sugar)
Hypoaesthesia (reduced sense of touch or sensation)
Hypokalaemia (low potassium)
Hypoxia (low oxygen in tissues)
Impaired healing
Infection
Inflammation
Injury
Jaw fracture
Laryngitis (inflammation of the larynx)

male:

Drug exposure during pregnancy
Apnoea (suspension of external breathing)
Injection site pruritus (severe itching at injection site)
Injection site reaction
Injection site swelling
Injection site warmth
Diabetes mellitus (diabetes, caused by a deficiency of the pancreatic hormone insulin)
Diabetes with hyperosmolarity (diabetes with increasing blood glucose levels and dehydration)
Hallucination (an experience involving the perception of something not present)
Hallucination, visual (seeing things that aren't there)

What are the common drug interactions of Effexor and Estazolam, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

Nausea (feeling of having an urge to vomit)
Abdominal pain
Cholecystitis acute (rapid infection of gallbladder)
Cholecystitis chronic (long lasting infection of gallbladder)
Cholelithiasis (the presence or formation of gallstones in the gallbladder or bile ducts)
Gallbladder injury
Hypertension (high blood pressure)
Intentional self-injury
Liver injury
Muscle injury

30-39:

Affect lability (emotional incontinence)
Intentional self-injury
Irritability

40-49:

Diabetic ketoacidosis (diabetic ketoacidosis (dka) is high concentrations of ketone bodies)
Lactic acidosis (low ph in body tissues)
Dehydration (dryness resulting from the removal of water)
Altered state of consciousness (altered state of mind)
Blood glucose increased
Decreased appetite
Pyrexia (fever)
Urinary tract infection
Escherichia urinary tract infection (urinary tract infection by escherichia coli)
Diabetes mellitus (diabetes, caused by a deficiency of the pancreatic hormone insulin)

50-59:

Fatigue (feeling of tiredness)
Headache (pain in head)
Increased appetite
Liver disorder (liver diseases)
Malaise (a feeling of general discomfort or uneasiness)
Metabolic acidosis (body produces too much acid, or when the kidneys are not removing enough acid from the body)
Oedema peripheral (superficial swelling)
Rash
Somnolence (a state of near-sleep, a strong desire for sleep)
Thoracic vertebral fracture

60+:

Anaphylactic shock (severe and rapid and sometimes fatal hypersensitivity reaction to a substance)
Hallucination (an experience involving the perception of something not present)
Hallucination, visual (seeing things that aren't there)

What are the existing conditions these people have? *

High Blood Pressure: 12 people, 28.57%
Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 12 people, 28.57%
Urticaria (rash of round, red welts on the skin that itch intensely): 11 people, 26.19%
Type 2 Diabetes: 11 people, 26.19%
Neurogenic Bladder (the normal function of the bladder is to store and empty urine in a coordinated, controlled fashion): 11 people, 26.19%
Hyperlipidaemia (presence of excess lipids in the blood): 11 people, 26.19%
Headache (pain in head): 11 people, 26.19%
Constipation: 11 people, 26.19%
Pain: 7 people, 16.67%
Sleep Disorder: 5 people, 11.90%

* Approximation only. Some reports may have incomplete information.

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