Amlodipine and Methylfolate drug interactions - a phase IV clinical study of FDA data
Summary:
Drug interactions are reported among people who take Amlodipine (amlodipine besylate) and Methylfolate (folic acid). Common drug interactions include sinusitis among females and anxiety among males.
The phase IV clinical study analyzes what interactions people have when they take Amlodipine and Methylfolate. It is created by eHealthMe based on reports of 42 people who take the same drugs from the FDA, and is updated regularly.
What is Amlodipine?
Amlodipine has active ingredients of amlodipine besylate. It is often used in high blood pressure. eHealthMe is studying from 354,829 Amlodipine users. Check the latest studies of Amlodipine.
What is Methylfolate?
Methylfolate has active ingredients of folic acid. eHealthMe is studying from 1,018 Methylfolate users. Check the latest studies of Methylfolate.
42 people who take Amlodipine and Methylfolate together, and have interactions are studied.

What are the common drug interactions of Amlodipine and Methylfolate, by gender? *:
female:
- Sinusitis (inflammation of sinus)
- Oral fungal infection
- Migraine (headache)
- Oropharyngeal pain
- Fall
- Limb injury
- Oedema (fluid collection in tissue)
- Rash pruritic (redness with itching)
- Accident at home
- Fatigue (feeling of tiredness)
male:
- Anxiety
- Hypersomnia (excessive daytime sleepiness (eds))
- Death
- Decreased activity
- Diarrhoea
- Pollakiuria (abnormally frequent passage of relatively small quantities or urine)
- Pruritus (severe itching of the skin)
- Quality of life decreased
- Urticaria (rash of round, red welts on the skin that itch intensely)
- Abdominal pain upper
What are the common drug interactions of Amlodipine and Methylfolate, by age (0-1 to 60+)? *:
0-1:
n/a
2-9:
n/a
10-19:
n/a
20-29:
n/a
30-39:
n/a
40-49:
- Dysgeusia (disorder of the sense of taste)
- Infusion site pruritus (severe itching at infusion site)
- Infusion site urticaria (rash of round, red welts on the skin at infusion site)
- Oral disorder (mouth disease)
50-59:
- Anhedonia (inability to experience pleasure from activities usually found enjoyable)
- Anxiety
- Chronic kidney disease
- Decreased activity
- Emotional distress
- Impaired work ability
- Pain
- Pollakiuria (abnormally frequent passage of relatively small quantities or urine)
- Quality of life decreased
- Arthralgia (joint pain)
60+:
- Sinusitis (inflammation of sinus)
- Oropharyngeal pain
- Fall
- Limb injury
- Nephrolithiasis (calculi in the kidneys)
- Oedema (fluid collection in tissue)
- Rash pruritic (redness with itching)
- Arthritis (form of joint disorder that involves inflammation of one or more joints)
- Chronic kidney disease
- Death
What are the existing conditions these people have? *
- Immunodeficiency Common Variable: 6 people, 14.29%
- High Blood Cholesterol: 6 people, 14.29%
- Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 5 people, 11.90%
- Abdominal Discomfort: 5 people, 11.90%
- Migraine (headache): 4 people, 9.52%
- Diabetes: 4 people, 9.52%
- Primary Immunodeficiency Syndrome: 3 people, 7.14%
- Narcolepsy (brain's inability to regulate sleep-wake cycles normally): 3 people, 7.14%
- Muscle Spasms (muscle contraction): 3 people, 7.14%
- Multiple Sclerosis (a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath): 3 people, 7.14%
* Approximation only. Some reports may have incomplete information.
Do you take Amlodipine and Methylfolate?
- Personalize this study to your gender, age, symptoms and drugs
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously
Related studies:
Effectiveness of, side effects of, and alternative drugs to the 2 drugs:
- Amlodipine (354,829 reports)
- Methylfolate (1,018 reports)
Browse all drug interactions of Amlodipine and Methylfolate:
a b c d e f g h i j k l m n o p q r s t u v w x y zSub-studies by gender and age:
Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Browse all side effects of Amlodipine:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all side effects of Methylfolate:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Amlodipine and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Methylfolate and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zHow the study uses the data?
The study uses data from the FDA. It is based on amlodipine besylate and folic acid (the active ingredients of Amlodipine and Methylfolate, respectively), and Amlodipine and Methylfolate (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.
How to use the study?
DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.
Who is eHealthMe?
With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
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