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Effexor and Provocholine drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Effexor (venlafaxine hydrochloride) and Provocholine (methacholine chloride). Common drug interactions include areflexia among females.

The phase IV clinical study analyzes what interactions people have when they take Effexor and Provocholine. It is created by eHealthMe based on reports of 22 people who take the same drugs from the FDA, and is updated regularly.

What is Effexor?

Effexor has active ingredients of venlafaxine hydrochloride. It is often used in depression. eHealthMe is studying from 99,493 Effexor users. Check the latest studies of Effexor.

What is Provocholine?

Provocholine has active ingredients of methacholine chloride. eHealthMe is studying from 80 Provocholine users. Check the latest studies of Provocholine.

On Aug, 03, 2026

22 people who take Effexor and Provocholine together, and have interactions are studied.

Effexor and Provocholine drug interactions.

What are the common drug interactions of Effexor and Provocholine, by gender? *:

female:

  1. Areflexia (absence of a reflex)
  2. Arthralgia (joint pain)
  3. Hypoaesthesia oral (reduced sense of touch or sensation in mouth)
  4. Impaired healing
  5. Ingrowing nail
  6. Injury
  7. Intervertebral disc protrusion (spinal disc protrusion)
  8. Lumbar radiculopathy (radicular pain in the low back and legs)
  9. Metastases to bone (cancer spreads to bone)
  10. Mitral valve prolapse (heart's mitral valve doesn't work well)

male:

n/a

What are the common drug interactions of Effexor and Provocholine, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

n/a

50-59:

  1. Areflexia (absence of a reflex)
  2. Arthralgia (joint pain)
  3. Hypoaesthesia oral (reduced sense of touch or sensation in mouth)
  4. Impaired healing
  5. Ingrowing nail
  6. Injury
  7. Intervertebral disc protrusion (spinal disc protrusion)
  8. Lumbar radiculopathy (radicular pain in the low back and legs)
  9. Metastases to bone (cancer spreads to bone)
  10. Mitral valve prolapse (heart's mitral valve doesn't work well)

60+:

n/a

What are the existing conditions these people have? *

  1. Hypercalcaemia (elevated calcium (ca+) level in the blood): 22 people, 100.00%
  2. Breast Cancer Metastatic: 22 people, 100.00%
  3. Breast Cancer: 22 people, 100.00%

* Approximation only. Some reports may have incomplete information.

Do you take Effexor and Provocholine?

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Effexor and Provocholine:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Effexor:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Provocholine:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Effexor and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Provocholine and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

How the study uses the data?

The study uses data from the FDA. It is based on venlafaxine hydrochloride and methacholine chloride (the active ingredients of Effexor and Provocholine, respectively), and Effexor and Provocholine (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.

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