Effexor and Ramelteon drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Effexor (venlafaxine hydrochloride) and Ramelteon (ramelteon). Common drug interactions include diabetic ketoacidosis among females and suicidal ideation among males.

The phase IV clinical study analyzes what interactions people have when they take Effexor and Ramelteon. It is created by eHealthMe based on reports of 16 people who take the same drugs from the FDA, and is updated regularly.

What is Effexor?

Effexor has active ingredients of venlafaxine hydrochloride. It is often used in depression. eHealthMe is studying from 99,493 Effexor users. Check the latest studies of Effexor.

What is Ramelteon?

Ramelteon has active ingredients of ramelteon. It is often used in insomnia. eHealthMe is studying from 1,387 Ramelteon users. Check the latest studies of Ramelteon.

On Aug, 04, 2026

16 people who take Effexor and Ramelteon together, and have interactions are studied.

Effexor and Ramelteon drug interactions.

What are the common drug interactions of Effexor and Ramelteon, by gender? *:

female:

Diabetic ketoacidosis (diabetic ketoacidosis (dka) is high concentrations of ketone bodies)
Lactic acidosis (low ph in body tissues)
Hypoglycaemia (deficiency of glucose in the bloodstream)
Overdose
Serotonin syndrome (occurs when two drugs that affect the body's level of serotonin are taken together at the same time)
Depressed level of consciousness
Metabolic acidosis (body produces too much acid, or when the kidneys are not removing enough acid from the body)
Thoracic vertebral fracture
Urinary tract infection
Altered state of consciousness (altered state of mind)

male:

Suicidal ideation
Cardiac arrest
Rash pruritic (redness with itching)
Self injurious behaviour
Completed suicide (act of taking one's own life)
Hallucination (an experience involving the perception of something not present)
Logorrhoea (excessive, uncontrollable, or incoherent talkativeness)
Respiratory arrest (cessation of normal respiration due to failure of the lungs to function effectively)
Somnolence (a state of near-sleep, a strong desire for sleep)
Drug abuse

What are the common drug interactions of Effexor and Ramelteon, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

Cardiac arrest
Completed suicide (act of taking one's own life)
Respiratory arrest (cessation of normal respiration due to failure of the lungs to function effectively)
Agitation (state of anxiety or nervous excitement)
Electrocardiogram qt prolonged
Hypoglycaemia (deficiency of glucose in the bloodstream)
Overdose
Serotonin syndrome (occurs when two drugs that affect the body's level of serotonin are taken together at the same time)
Tonic convulsion (the person will quickly lose consciousness and the skeletal muscles will suddenly tense, often causing the extremities to be pulled towards the body or rigidly pushed away from it)
Tremor (trembling or shaking movements in one or more parts of your body)

30-39:

Overdose
Depressed level of consciousness
Drug abuse
Hypoglycaemia (deficiency of glucose in the bloodstream)
Serotonin syndrome (occurs when two drugs that affect the body's level of serotonin are taken together at the same time)
Akathisia (a movement disorder characterized by a feeling of inner restlessness)

40-49:

Lactic acidosis (low ph in body tissues)
Urinary tract infection
Escherichia urinary tract infection (urinary tract infection by escherichia coli)
Diabetic ketoacidosis (diabetic ketoacidosis (dka) is high concentrations of ketone bodies)

50-59:

Metabolic acidosis (body produces too much acid, or when the kidneys are not removing enough acid from the body)
Thoracic vertebral fracture
Altered state of consciousness (altered state of mind)
Depressed level of consciousness

60+:

Hallucination (an experience involving the perception of something not present)
Logorrhoea (excessive, uncontrollable, or incoherent talkativeness)
Somnolence (a state of near-sleep, a strong desire for sleep)
Suicidal ideation
Rash pruritic (redness with itching)

What are the existing conditions these people have? *

High Blood Pressure: 5 people, 31.25%
Bipolar I Disorder (mood disorder that is characterized by at least one manic or mixed episode): 5 people, 31.25%
Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 5 people, 31.25%
Hyperlipidaemia (presence of excess lipids in the blood): 4 people, 25.00%
Constipation: 4 people, 25.00%
Headache (pain in head): 4 people, 25.00%
Type 2 Diabetes: 4 people, 25.00%
Urticaria (rash of round, red welts on the skin that itch intensely): 4 people, 25.00%
Neurogenic Bladder (the normal function of the bladder is to store and empty urine in a coordinated, controlled fashion): 4 people, 25.00%
Pain: 4 people, 25.00%

* Approximation only. Some reports may have incomplete information.

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