Clopra and Compro drug interactions - a phase IV clinical study of FDA data
Summary:
Drug interactions are reported among people who take Clopra (metoclopramide hydrochloride) and Compro (prochlorperazine). Common drug interactions include areflexia among females and anxiety among males.
The phase IV clinical study analyzes what interactions people have when they take Clopra and Compro. It is created by eHealthMe based on reports of 43 people who take the same drugs from the FDA, and is updated regularly.
What is Clopra?
Clopra has active ingredients of metoclopramide hydrochloride. eHealthMe is studying from 81,430 Clopra users. Check the latest studies of Clopra.
What is Compro?
Compro has active ingredients of prochlorperazine. eHealthMe is studying from 197 Compro users. Check the latest studies of Compro.
43 people who take Clopra and Compro together, and have interactions are studied.

What are the common drug interactions of Clopra and Compro, by gender? *:
female:
- Areflexia (absence of a reflex)
- Arthralgia (joint pain)
- Back pain
- Bone disorder
- Cellulitis (infection under the skin)
- Cystocele (a condition that occurs when the tough fibrous wall between a woman's bladder and her vagina is torn by childbirth)
- Eating disorder
- Emotional distress
- Excessive granulation tissue (excessive collagen-rich tissue which forms at the site of an injury)
- Exostosis (formation of new bone on the surface of a bone)
male:
- Anxiety
- Injury
- Herpes zoster
- Lumbar spinal stenosis (a medical condition in which the spinal canal narrows and compresses the spinal cord and nerves at the level of the lumbar bone)
- Neck pain
- Oedema peripheral (superficial swelling)
- Spinal disorder (disease of spine a back bone)
- Type 2 diabetes mellitus
- Blindness transient (sudden loss of vision)
- Loss of consciousness
What are the common drug interactions of Clopra and Compro, by age (0-1 to 60+)? *:
0-1:
n/a
2-9:
n/a
10-19:
n/a
20-29:
n/a
30-39:
n/a
40-49:
n/a
50-59:
- Oedema peripheral (superficial swelling)
- Pain
- Bone pain
- Osteonecrosis of jaw (death of bone of jaw)
- Anaemia (lack of blood)
- Pyrexia (fever)
- Osteoarthritis (a joint disease caused by cartilage loss in a joint)
- Eye pain
- Muscular weakness (muscle weakness)
- Paraesthesia (sensation of tingling, tickling, prickling, pricking, or burning of a person's skin with no apparent long-term physical effect)
60+:
- Affective disorder (mental disorder)
- Anaemia (lack of blood)
- Blood immunoglobulin a increased
- Bone fistula
- Bone pain
- Breast pain
- Breast swelling
- Cardiomegaly (increased size of heart than normal)
- Cataract (clouding of the lens inside the eye)
- Chest pain
What are the existing conditions these people have? *
- Hypercalcaemia (elevated calcium (ca+) level in the blood): 16 people, 37.21%
- Breast Cancer: 16 people, 37.21%
- Breast Cancer Metastatic: 15 people, 34.88%
- Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 5 people, 11.63%
- Stress And Anxiety: 4 people, 9.30%
- Stable Angina (a constant chest pain): 4 people, 9.30%
- Neuralgia (pain in one or more nerves): 4 people, 9.30%
- Diabetes: 4 people, 9.30%
- Depression: 4 people, 9.30%
- Migraine (headache): 3 people, 6.98%
* Approximation only. Some reports may have incomplete information.
Do you take Clopra and Compro?
- Personalize this study to your gender, age, symptoms and drugs
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously
Related studies:
Effectiveness of, side effects of, and alternative drugs to the 2 drugs:
Browse all drug interactions of Clopra and Compro:
a b c d e f g h i j k l m n o p q r s t u v w x y zSub-studies by gender and age:
Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Browse all side effects of Clopra:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all side effects of Compro:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Clopra and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Compro and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zHow the study uses the data?
The study uses data from the FDA. It is based on metoclopramide hydrochloride and prochlorperazine (the active ingredients of Clopra and Compro, respectively), and Clopra and Compro (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.
How to use the study?
DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.
Who is eHealthMe?
With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.
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