Effexor and Tacrolimus drug interactions - a phase IV clinical study of FDA data
Summary:
Drug interactions are reported among people who take Effexor (venlafaxine hydrochloride) and Tacrolimus (tacrolimus). Common drug interactions include urinary tract infection among females and gait disturbance among males.
The phase IV clinical study analyzes what interactions people have when they take Effexor and Tacrolimus. It is created by eHealthMe based on reports of 82 people who take the same drugs from the FDA, and is updated regularly.
What is Effexor?
Effexor has active ingredients of venlafaxine hydrochloride. It is often used in depression. eHealthMe is studying from 99,493 Effexor users. Check the latest studies of Effexor.
What is Tacrolimus?
Tacrolimus has active ingredients of tacrolimus. It is often used in kidney transplant. eHealthMe is studying from 116,160 Tacrolimus users. Check the latest studies of Tacrolimus.
82 people who take Effexor and Tacrolimus together, and have interactions are studied.

What are the common drug interactions of Effexor and Tacrolimus, by gender? *:
female:
- Urinary tract infection
- Arthralgia (joint pain)
- Fall
- Weight decreased
- Fatigue (feeling of tiredness)
- Cytomegalovirus infection
- Headache (pain in head)
- Hypokalaemia (low potassium)
- Irritable bowel syndrome
- Pain
male:
- Gait disturbance
- Pain
- Back pain
- Pruritus (severe itching of the skin)
- Alopecia (absence of hair from areas of the body)
- Blister (small pocket of fluid within the upper layers of the skin caused by forceful rubbing (friction), burning, freezing, chemical exposure)
- Bone pain
- Dry skin
- Dyspnoea (difficult or laboured respiration)
- Fatigue (feeling of tiredness)
What are the common drug interactions of Effexor and Tacrolimus, by age (0-1 to 60+)? *:
0-1:
n/a
2-9:
n/a
10-19:
n/a
20-29:
- Blood pressure increased
- Bone marrow disorder
- Diarrhoea
- Diffuse large b-cell lymphoma stage iii (cancer of b cells, a type of white blood cell-stage iii)
- Gastrooesophageal reflux disease (stomach contents (food or liquid) leak backwards from the stomach into the oesophagus)
- Insomnia (sleeplessness)
- Lung disorder (lung disease)
- Lymphadenopathy (disease or enlargement of lymph nodes)
- Lymphoma (cancer that begins in immune system cells)
- Nausea (feeling of having an urge to vomit)
30-39:
- Blood parathyroid hormone increased
- Blood glucose increased
- Bradycardia (abnormally slow heart action)
- Bronchial fistula
- Cardiac arrest
- Diarrhoea
- Empyema (collection of pus in a cavity in the body)
- Gastroenteritis (inflammation of stomach and intestine)
- Haemoglobin decreased
- Hydropneumothorax (presence of both air and fluid in the pleural space (lungs))
40-49:
- Adrenal insufficiency (a condition in which the adrenal glands do not produce adequate amounts of steroids)
- Blood pressure decreased
- Dehydration (dryness resulting from the removal of water)
- Dizziness
- Haematocrit decreased
- Haemoglobin decreased
- Red blood cell count decreased
- White blood cell count decreased
- Agitation (state of anxiety or nervous excitement)
- Amnesia (deficit in memory caused by brain damage, disease, or psychological trauma)
50-59:
- Joint swelling
- Left ventricular failure (left ventricle fails to contract forcefully)
- Major depression (a mood state that goes well beyond temporarily feeling sad or blue. it is a serious medical illness that affects one's thoughts, feelings)
- Muscle spasms (muscle contraction)
- Myalgia (muscle pain)
- Neck pain
- Neuropathy peripheral (surface nerve damage)
- Pain
- Peripheral swelling
- Pulmonary hypertension (increase in blood pressure in the lung artery)
60+:
- Pain
- Arthralgia (joint pain)
- Fatigue (feeling of tiredness)
- Gait disturbance
- Hyperkeratosis (thickening of the outer layer of the skin)
- Joint instability (a condition in which the joints aren't sufficiently supported)
- Joint range of motion decreased (disease of joint movement)
- Joint stiffness
- Mobility decreased (ability to move is reduced)
- Muscular weakness (muscle weakness)
What are the existing conditions these people have? *
- Polymyalgia Rheumatica (pain in many muscles): 9 people, 10.98%
- Bronchospasm (spasm of bronchial smooth muscle producing narrowing of the bronchi): 9 people, 10.98%
- Anaemia (lack of blood): 9 people, 10.98%
- Immunodeficiency Common Variable: 8 people, 9.76%
- Lipidosis (disorder of lipid metabolism involving abnormal accumulation of lipids in the reticuloendothelial cells): 6 people, 7.32%
- Immune System Disorder: 6 people, 7.32%
- Inflammation: 5 people, 6.10%
* Approximation only. Some reports may have incomplete information.
Do you take Effexor and Tacrolimus?
- Personalize this study to your gender, age, symptoms and drugs
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously
Related studies:
Effectiveness of, side effects of, and alternative drugs to the 2 drugs:
- Effexor (99,493 reports)
- Tacrolimus (116,160 reports)
Browse all drug interactions of Effexor and Tacrolimus:
a b c d e f g h i j k l m n o p q r s t u v w x y zSub-studies by gender and age:
Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Browse all side effects of Effexor:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all side effects of Tacrolimus:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Effexor and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Tacrolimus and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zHow the study uses the data?
The study uses data from the FDA. It is based on venlafaxine hydrochloride and tacrolimus (the active ingredients of Effexor and Tacrolimus, respectively), and Effexor and Tacrolimus (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.
How to use the study?
DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.
Who is eHealthMe?
With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.
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