Ultram and Meprobamate drug interactions - a phase IV clinical study of FDA data
Summary:
Drug interactions are reported among people who take Ultram (tramadol hydrochloride) and Meprobamate (meprobamate). Common drug interactions include overdose among females and completed suicide among males.
The phase IV clinical study analyzes what interactions people have when they take Ultram and Meprobamate. It is created by eHealthMe based on reports of 15 people who take the same drugs from the FDA, and is updated regularly.
What is Ultram?
Ultram has active ingredients of tramadol hydrochloride. It is often used in pain. eHealthMe is studying from 28,425 Ultram users. Check the latest studies of Ultram.
What is Meprobamate?
Meprobamate has active ingredients of meprobamate. It is often used in stress and anxiety. eHealthMe is studying from 2,268 Meprobamate users. Check the latest studies of Meprobamate.
15 people who take Ultram and Meprobamate together, and have interactions are studied.

What are the common drug interactions of Ultram and Meprobamate, by gender? *:
female:
- Overdose
- Affective disorder (mental disorder)
- Cardio-respiratory arrest (sudden dysfunction of heart and lungs)
- Dizziness
- Drug abuser
- Hypoaesthesia (reduced sense of touch or sensation)
- Paraesthesia (sensation of tingling, tickling, prickling, pricking, or burning of a person's skin with no apparent long-term physical effect)
- Abdominal pain
- Alcohol poisoning
- Altered state of consciousness (altered state of mind)
male:
- Completed suicide (act of taking one's own life)
- Depression
- Activities of daily living impaired
- Atrophy (wasting away of a part of the body)
- Diarrhoea
- Gastroenteritis (inflammation of stomach and intestine)
- Gastrointestinal disorder (functional problems of gastrointestinal tract)
- Injury
- Insomnia (sleeplessness)
- Intervertebral disc protrusion (spinal disc protrusion)
What are the common drug interactions of Ultram and Meprobamate, by age (0-1 to 60+)? *:
0-1:
n/a
2-9:
n/a
10-19:
n/a
20-29:
- Gastrointestinal disorder (functional problems of gastrointestinal tract)
- Lower respiratory tract infection
- Overdose
- Pulmonary oedema (fluid accumulation in the lungs)
- Suicide attempt
30-39:
- Completed suicide (act of taking one's own life)
- Depression
- Drug ineffective
- Activities of daily living impaired
- Atrophy (wasting away of a part of the body)
- Cellulitis (infection under the skin)
- Drug toxicity
- Erectile dysfunction
- Faecal incontinence (a lack of control over passing stool)
- Injury
40-49:
- Completed suicide (act of taking one's own life)
- Diarrhoea
- Gastroenteritis (inflammation of stomach and intestine)
50-59:
- Hypoaesthesia (reduced sense of touch or sensation)
- Paraesthesia (sensation of tingling, tickling, prickling, pricking, or burning of a person's skin with no apparent long-term physical effect)
- Abdominal pain
- Alcohol poisoning
- Altered state of consciousness (altered state of mind)
- Conjunctival hyperaemia (congestion of conjunctival vessels)
- Dehydration (dryness resulting from the removal of water)
- Delirium (wild excitement)
- Dizziness
- Drug abuse
60+:
- Dizziness
- Drug hypersensitivity
- Dysphagia (a condition in which swallowing is difficult or painful)
- Hemiparesis (weakness on one side of the body)
- Peripheral swelling
- Thrombotic stroke (stroke due to clot formation)
What are the existing conditions these people have? *
- Sleep Disorder: 3 people, 20.00%
- Erection Problems: 2 people, 13.33%
- Myelodysplastic Syndrome (a group of conditions that occur when the blood-forming cells in the bone marrow are damaged): 1 person, 6.67%
- Muscle Spasms (muscle contraction): 1 person, 6.67%
- Muscle Aches (muscle pain): 1 person, 6.67%
- Lung Neoplasm Malignant (cancer tumour of lung): 1 person, 6.67%
- Ill-Defined Disorder: 1 person, 6.67%
- High Blood Pressure: 1 person, 6.67%
- Gastric Disorder (disease of stomach): 1 person, 6.67%
- Fibromyalgia (a long-term condition which causes pain all over the body): 1 person, 6.67%
* Approximation only. Some reports may have incomplete information.
Do you take Ultram and Meprobamate?
- Personalize this study to your gender, age, symptoms and drugs
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously
Related studies:
Effectiveness of, side effects of, and alternative drugs to the 2 drugs:
- Ultram (28,425 reports)
- Meprobamate (2,268 reports)
Browse all drug interactions of Ultram and Meprobamate:
a b c d e f g h i j k l m n o p q r s t u v w x y zSub-studies by gender and age:
Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Browse all side effects of Ultram:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all side effects of Meprobamate:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Ultram and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Meprobamate and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zRelated publications that referenced our studies
- Mansour HM, "Tramadol and Disseminated Intravascular Coagulopathy: A Case Report", Medicine Science, 2015 Jan .
- Mansour HM, "Tramadol and Disseminated Intravascular Coagulopathy: A Case Report", Medicine Science, 2015 Jan .
How the study uses the data?
The study uses data from the FDA. It is based on tramadol hydrochloride and meprobamate (the active ingredients of Ultram and Meprobamate, respectively), and Ultram and Meprobamate (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.
How to use the study?
DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.
Who is eHealthMe?
With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.
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