Effient and Plaquenil drug interactions - a phase IV clinical study of FDA data
Summary:
Drug interactions are reported among people who take Effient (prasugrel hydrochloride) and Plaquenil (hydroxychloroquine sulfate). Common drug interactions include nausea among females and abdominal pain among males.
The phase IV clinical study analyzes what interactions people have when they take Effient and Plaquenil. It is created by eHealthMe based on reports of 26 people who take the same drugs from the FDA, and is updated regularly.
What is Effient?
Effient has active ingredients of prasugrel hydrochloride. It is often used in stent. eHealthMe is studying from 9,482 Effient users. Check the latest studies of Effient.
What is Plaquenil?
Plaquenil has active ingredients of hydroxychloroquine sulfate. It is often used in systemic lupus erythematosus. eHealthMe is studying from 91,018 Plaquenil users. Check the latest studies of Plaquenil.
26 people who take Effient and Plaquenil together, and have interactions are studied.

What are the common drug interactions of Effient and Plaquenil, by gender? *:
female:
- Nausea (feeling of having an urge to vomit)
- Drug ineffective
- Fall
- Acne (skin problems that cause pimples)
- Humerus fracture (injury to the upper arm bone)
- Inflammation
- Injection site bruising
- Injection site pain
- Intestinal perforation (complete penetration of the wall of the intestine)
- Oedema (fluid collection in tissue)
male:
- Abdominal pain
- Amylase increased
- Vomiting
- Atrial fibrillation (fibrillation of the muscles of the atria of the heart)
- Burning sensation
- Epistaxis (bleed from the nose)
- Erythema (redness of the skin)
- Flushing (the warm, red condition of human skin)
- Hypertension (high blood pressure)
- Nephrolithiasis (calculi in the kidneys)
What are the common drug interactions of Effient and Plaquenil, by age (0-1 to 60+)? *:
0-1:
n/a
2-9:
n/a
10-19:
n/a
20-29:
n/a
30-39:
n/a
40-49:
n/a
50-59:
- Fall
- Humerus fracture (injury to the upper arm bone)
- Myocardial infarction (destruction of heart tissue resulting from obstruction of the blood supply to the heart muscle)
- Arthritis (form of joint disorder that involves inflammation of one or more joints)
- Cardiac disorder
- Chronic obstructive pulmonary disease (a progressive disease that makes it hard to breathe)
- Dizziness
- Fatigue (feeling of tiredness)
- Infection
- Injection site bruising
60+:
- Drug ineffective
- Nausea (feeling of having an urge to vomit)
- Rash
- Scab (a hard coating on the skin formed during the wound healing)
- Mallet finger (a deformity of a finger caused when a certain tendon (the extensor tendon) is damaged)
- Pneumonia legionella (pneumonia caused by the bacteria legionella)
- Synovitis (inflammation of the synovial membrane)
- Benign neoplasm (benign (non-cancerous) tumour)
- Bladder mass
- Coronary artery occlusion (complete obstruction of blood flow in a coronary artery)
What are the existing conditions these people have? *
- Rheumatoid Arthritis (a chronic progressive disease causing inflammation in the joints): 17 people, 65.38%
- Pain: 3 people, 11.54%
- Diabetes: 3 people, 11.54%
- Narcolepsy (brain's inability to regulate sleep-wake cycles normally): 2 people, 7.69%
- Insomnia (sleeplessness): 2 people, 7.69%
- Hypoaesthesia (reduced sense of touch or sensation): 2 people, 7.69%
- High Blood Cholesterol: 2 people, 7.69%
- Depression: 2 people, 7.69%
- Cardiac Disorder: 2 people, 7.69%
* Approximation only. Some reports may have incomplete information.
Do you take Effient and Plaquenil?
- Personalize this study to your gender, age, symptoms and drugs
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously
Related studies:
Effectiveness of, side effects of, and alternative drugs to the 2 drugs:
Browse all drug interactions of Effient and Plaquenil:
a b c d e f g h i j k l m n o p q r s t u v w x y zSub-studies by gender and age:
Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Browse all side effects of Effient:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all side effects of Plaquenil:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Effient and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Plaquenil and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zHow the study uses the data?
The study uses data from the FDA. It is based on prasugrel hydrochloride and hydroxychloroquine sulfate (the active ingredients of Effient and Plaquenil, respectively), and Effient and Plaquenil (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.
How to use the study?
DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.
Who is eHealthMe?
With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.
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