Efudex and Seroquel drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Efudex (fluorouracil) and Seroquel (quetiapine fumarate). Common drug interactions include blood pressure increased among females and anxiety among males.

The phase IV clinical study analyzes what interactions people have when they take Efudex and Seroquel. It is created by eHealthMe based on reports of 11 people who take the same drugs from the FDA, and is updated regularly.

What is Efudex?

Efudex has active ingredients of fluorouracil. It is often used in actinic keratosis. eHealthMe is studying from 1,391 Efudex users. Check the latest studies of Efudex.

What is Seroquel?

Seroquel has active ingredients of quetiapine fumarate. It is often used in bipolar disorder. eHealthMe is studying from 120,285 Seroquel users. Check the latest studies of Seroquel.

On Jul, 19, 2026

11 people who take Efudex and Seroquel together, and have interactions are studied.

What are the common drug interactions of Efudex and Seroquel, by gender? *:

female:

Blood pressure increased
Asthma
Hypoglycaemia (deficiency of glucose in the bloodstream)
Neuropathy peripheral (surface nerve damage)
Pulmonary mass
Surgery
Vulvovaginal pain
Adjustment disorder with depressed mood
Asthenia (weakness)
Cough

male:

Anxiety
Appetite disorder (abnormal eating habits)
Pericarditis (inflammation of the pericardium)
Pneumonia aspiration (bronchopneumonia that develops due to the entrance of foreign materials into the bronchial tree)
Pulmonary mass
Skin disorder (skin disease)
White blood cell count decreased
Cognitive disorder (mental health disorders affects learning, memory, perception, and problem solving)
Communication disorder (speech and language disorder)
Death

What are the common drug interactions of Efudex and Seroquel, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

Disturbance in attention
Dizziness
Fatigue (feeling of tiredness)
Headache (pain in head)
Hypoaesthesia (reduced sense of touch or sensation)
Malaise (a feeling of general discomfort or uneasiness)
Oropharyngeal pain
Pain in extremity
Paraesthesia (sensation of tingling, tickling, prickling, pricking, or burning of a person's skin with no apparent long-term physical effect)
Throat irritation

50-59:

Anxiety
Blood pressure increased
Delusion (a false belief or opinion)

60+:

Alopecia (absence of hair from areas of the body)
Death
Pericarditis (inflammation of the pericardium)
Psychological trauma

What are the existing conditions these people have? *

Narcolepsy (brain's inability to regulate sleep-wake cycles normally): 5 people, 45.45%
Relapsing-Remitting Multiple Sclerosis (reoccurrence of an inflammatory disease in which the insulating covers of nerve cells in the brain and spinal cord are damaged): 2 people, 18.18%
Insomnia (sleeplessness): 2 people, 18.18%
Hypothyroidism (abnormally low activity of the thyroid gland, resulting in retardation of growth and mental development): 2 people, 18.18%
Generalized Anxiety Disorder (excessive, uncontrollable, unexplained and often irrational worry): 2 people, 18.18%
Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 2 people, 18.18%
Thrombocytopenia (decrease of platelets in blood): 1 person, 9.09%
Stress And Anxiety: 1 person, 9.09%
Pain: 1 person, 9.09%
Nausea And Vomiting: 1 person, 9.09%

* Approximation only. Some reports may have incomplete information.

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