Elidel and Prednisolone drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Elidel (pimecrolimus) and Prednisolone (prednisolone). Common drug interactions include osteomyelitis among females and dermatitis atopic among males.

The phase IV clinical study analyzes what interactions people have when they take Elidel and Prednisolone. It is created by eHealthMe based on reports of 46 people who take the same drugs from the FDA, and is updated regularly.

What is Elidel?

Elidel has active ingredients of pimecrolimus. It is often used in eczema. eHealthMe is studying from 5,201 Elidel users. Check the latest studies of Elidel.

What is Prednisolone?

Prednisolone has active ingredients of prednisolone. It is often used in rheumatoid arthritis. eHealthMe is studying from 212,675 Prednisolone users. Check the latest studies of Prednisolone.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.



On Sep, 01, 2026

46 people who take Elidel and Prednisolone together, and have interactions are studied.

Elidel and Prednisolone drug interactions.

What are the common drug interactions of Elidel and Prednisolone, by gender? *:

female:

  1. Osteomyelitis (infection of bone)
  2. Osteonecrosis (death of bone)
  3. Pain
  4. Pain in extremity
  5. Pain in jaw
  6. Papilloma (small, noncancerous (benign) tumour)
  7. Primary sequestrum (piece of dead bone that has become separated during the process of necrosis from normal/sound bone)
  8. Procedural pain
  9. Psychological trauma
  10. Purulent discharge (discharge that contains pus)

male:

  1. Dermatitis atopic (inflammatory, chronically relapsing, non-contagious and pruritic skin disorder)
  2. Rash
  3. Pruritus (severe itching of the skin)
  4. Rash maculo-papular (red area on the skin that is covered with small confluent bumps)
  5. Sudden onset of sleep
  6. Vomiting
  7. Erysipelas (bacterial skin infection)
  8. Body mass index increased
  9. Cerebral ischaemia (insufficient blood flow to the brain to meet metabolic demand)
  10. Chest pain

What are the common drug interactions of Elidel and Prednisolone, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

  1. Adrenal disorder
  2. Dry skin
  3. Erythema (redness of the skin)
  4. Fatigue (feeling of tiredness)
  5. Hypotension (abnormally low blood pressure)
  6. Poor quality sleep
  7. Skin exfoliation (removal of the oldest dead skin cells)
  8. Skin swelling
  9. Steroid withdrawal syndrome (dizziness, fatigue, gastrointestinal problems, and headaches after stop taking steroids)
  10. Temperature regulation disorder (body is unable to maintain temperature)

20-29:

n/a

30-39:

  1. Vertigo
  2. Visual impairment
  3. Dermatitis atopic (inflammatory, chronically relapsing, non-contagious and pruritic skin disorder)
  4. Headache (pain in head)
  5. Rash
  6. Disease recurrence
  7. Eosinophil count increased
  8. General physical health deterioration (weak health status)
  9. Nausea (feeling of having an urge to vomit)
  10. Pruritus (severe itching of the skin)

40-49:

  1. Sudden onset of sleep
  2. Breast cancer metastatic
  3. Cerebral ischaemia (insufficient blood flow to the brain to meet metabolic demand)
  4. Convulsion (muscles contract and relax rapidly and repeatedly, resulting in an uncontrolled shaking of the body)
  5. Death
  6. Epilepsy (common and diverse set of chronic neurological disorders characterized by seizures)
  7. Impaired work ability
  8. Muscle tightness
  9. Nervous system disorder (a general class of medical conditions affecting the nervous system)
  10. Somnolence (a state of near-sleep, a strong desire for sleep)

50-59:

  1. Alopecia (absence of hair from areas of the body)
  2. Diarrhoea
  3. Haematuria (presence of blood in urine)
  4. Iga nephropathy (kidney disease- condition prevents the kidneys from filtering waste)
  5. Psychological trauma
  6. Rash
  7. Renal failure (kidney dysfunction)
  8. Renal injury (kidney injury)

60+:

  1. Injection site pruritus (severe itching at injection site)
  2. Rash
  3. Anhedonia (inability to experience pleasure from activities usually found enjoyable)
  4. Anxiety
  5. Back pain
  6. Body mass index increased
  7. Bone disorder
  8. Bone pain
  9. Colon cancer
  10. Deformity (disfigurement)

What are the existing conditions these people have? *

  1. Rashes (redness): 11 people, 23.91%
  2. Dermatitis Atopic (inflammatory, chronically relapsing, non-contagious and pruritic skin disorder): 11 people, 23.91%
  3. High Blood Pressure: 10 people, 21.74%
  4. Muscle Spasms (muscle contraction): 7 people, 15.22%
  5. Joint Pain: 6 people, 13.04%
  6. Asthma: 6 people, 13.04%
  7. Actinic Keratosis (skin disease due to sun exposure): 5 people, 10.87%
  8. Dermatitis Allergic (inflammation of the skin due allergic reaction): 5 people, 10.87%
  9. Cough: 5 people, 10.87%
  10. Hypothyroidism (abnormally low activity of the thyroid gland, resulting in retardation of growth and mental development): 5 people, 10.87%

* Approximation only. Some reports may have incomplete information.

Do you take Elidel and Prednisolone?

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Elidel and Prednisolone:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Elidel:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Prednisolone:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Elidel and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Prednisolone and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Related publications that referenced our studies


How the study uses the data?

The study uses data from the FDA. It is based on pimecrolimus and prednisolone (the active ingredients of Elidel and Prednisolone, respectively), and Elidel and Prednisolone (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



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