Eligard and Dostinex drug interactions - a phase IV clinical study of FDA data
Summary:
Drug interactions are reported among people who take Eligard (leuprolide acetate) and Dostinex (cabergoline). Common drug interactions include injection site pain among males.
The phase IV clinical study analyzes what interactions people have when they take Eligard and Dostinex. It is created by eHealthMe based on reports of 21 people who take the same drugs from the FDA, and is updated regularly.
What is Eligard?
Eligard has active ingredients of leuprolide acetate. It is often used in prostate cancer. eHealthMe is studying from 44,652 Eligard users. Check the latest studies of Eligard.
What is Dostinex?
Dostinex has active ingredients of cabergoline. It is often used in prolactinoma. eHealthMe is studying from 3,064 Dostinex users. Check the latest studies of Dostinex.
21 people who take Eligard and Dostinex together, and have interactions are studied.

What are the common drug interactions of Eligard and Dostinex, by gender? *:
female:
n/a
male:
- Injection site pain
- Headache (pain in head)
- Movement disorder (neurological syndromes where they may be excess of movement or a paucity of movement that is not connected to weakness)
- Musculoskeletal stiffness (stiffness of the body's muscles, joints, tendons, ligaments and nerves)
- Oedema peripheral (superficial swelling)
- Oncologic complication
- Pain in extremity
- Productive cough
- Prostatic specific antigen increased
- Pruritus (severe itching of the skin)
What are the common drug interactions of Eligard and Dostinex, by age (0-1 to 60+)? *:
0-1:
n/a
2-9:
n/a
10-19:
n/a
20-29:
n/a
30-39:
n/a
40-49:
n/a
50-59:
- Injection site pain
- Headache (pain in head)
- Movement disorder (neurological syndromes where they may be excess of movement or a paucity of movement that is not connected to weakness)
- Musculoskeletal stiffness (stiffness of the body's muscles, joints, tendons, ligaments and nerves)
- Oedema peripheral (superficial swelling)
- Oncologic complication
- Pain in extremity
- Productive cough
- Prostatic specific antigen increased
- Pruritus (severe itching of the skin)
60+:
n/a
What are the existing conditions these people have? *
- High Blood Pressure: 21 people, 100.00%
- Acromegaly (body produces too much growth hormone, leading to excess growth of body tissues): 19 people, 90.48%
- Carcinoid Tumor: 18 people, 85.71%
* Approximation only. Some reports may have incomplete information.
Do you take Eligard and Dostinex?
- Personalize this study to your gender, age, symptoms and drugs
- Predict drug outcomes for up to one year with AI
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Related studies:
Effectiveness of, side effects of, and alternative drugs to the 2 drugs:
Browse all drug interactions of Eligard and Dostinex:
a b c d e f g h i j k l m n o p q r s t u v w x y zSub-studies by gender and age:
Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Browse all side effects of Eligard:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all side effects of Dostinex:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Eligard and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Dostinex and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zRelated publications that referenced our studies
- Sharma SP, Muggia F, "Supraventricular tachycardia and urticaria complicating leuprolide-induced ovarian suppression in a young woman with breast cancer: a case report", ecancermedicalscience, 2016 Jan .
- Pong YH, Lu YC, Tsai VF, Huang PL, Hsieh JT, Chang HC, "Acute manic and psychotic symptoms following subcutaneous leuprolide acetate in a male patient without prior psychiatric history: A case report and literature review", Urological Science, 2014 Mar .
- Gürbüz F, Ya?c?-Küpeli B, K?r Y, Yüksel B, Zorludemir S, Gürbüz BB, Küpeli S, "The first report of cabergoline-induced immune hemolytic anemia in an adolescent with prolactinoma", Journal of Pediatric Endocrinology and Metabolism, 2014 Jan .
- Harris YT, Harris AZ, "Cabergoline associated with first episode mania", Psychosomatics, 2012 Jan .
- Sharma SP, Muggia F, "Supraventricular tachycardia and urticaria complicating leuprolide-induced ovarian suppression in a young woman with breast cancer: a case report", ecancermedicalscience, 2016 Jan .
- Pong YH, Lu YC, Tsai VF, Huang PL, Hsieh JT, Chang HC, "Acute manic and psychotic symptoms following subcutaneous leuprolide acetate in a male patient without prior psychiatric history: A case report and literature review", Urological Science, 2014 Mar .
- Gürbüz F, Ya?c?-Küpeli B, K?r Y, Yüksel B, Zorludemir S, Gürbüz BB, Küpeli S, "The first report of cabergoline-induced immune hemolytic anemia in an adolescent with prolactinoma", Journal of Pediatric Endocrinology and Metabolism, 2014 Jan .
- Harris YT, Harris AZ, "Cabergoline associated with first episode mania", Psychosomatics, 2012 Jan .
How the study uses the data?
The study uses data from the FDA. It is based on leuprolide acetate and cabergoline (the active ingredients of Eligard and Dostinex, respectively), and Eligard and Dostinex (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.
How to use the study?
DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.
Who is eHealthMe?
With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.
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