Eliquis and Plendil drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Eliquis (apixaban) and Plendil (felodipine). Common drug interactions include faeces hard among females and metastases to spine among males.

The phase IV clinical study analyzes what interactions people have when they take Eliquis and Plendil. It is created by eHealthMe based on reports of 11 people who take the same drugs from the FDA, and is updated regularly.

What is Eliquis?

Eliquis has active ingredients of apixaban. It is often used in atrial fibrillation/flutter. eHealthMe is studying from 191,864 Eliquis users. Check the latest studies of Eliquis.

What is Plendil?

Plendil has active ingredients of felodipine. It is often used in high blood pressure. eHealthMe is studying from 4,990 Plendil users. Check the latest studies of Plendil.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Sep, 03, 2026

11 people who take Eliquis and Plendil together, and have interactions are studied.

What are the common drug interactions of Eliquis and Plendil, by gender? *:

female:

Faeces hard
Therapeutic response unexpected
Diarrhoea
Dizziness
Dysstasia (difficulty in standing)
Muscular weakness (muscle weakness)
Visual acuity reduced (reduced clearness of vision)

male:

Metastases to spine (cancer spreads to spine)
Prostatic specific antigen increased
Terminal state (the transitional states between life and biological death)
Aortic aneurysm (enlargement of an aortic artery caused by a weakening of the artery wall)
Back pain
Circulatory collapse
Dyspnoea (difficult or laboured respiration)
Iliac artery stenosis (the abnormal narrowing of a iliac artery)
Metastases to bone (cancer spreads to bone)
Metastases to liver (cancer spreads to liver)

What are the common drug interactions of Eliquis and Plendil, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

n/a

50-59:

n/a

60+:

Faeces hard
Therapeutic response unexpected
Circulatory collapse
Dyspnoea (difficult or laboured respiration)
Iliac artery stenosis (the abnormal narrowing of a iliac artery)
Metastases to bone (cancer spreads to bone)
Metastases to liver (cancer spreads to liver)
Staphylococcal bacteraemia (a bacterial infection of blood)
Terminal state (the transitional states between life and biological death)
Visual acuity reduced (reduced clearness of vision)

What are the existing conditions these people have? *

Barrett's Oesophagus (barrett's oesophagus is a disorder in which the lining of the oesophagus (the tube that carries food from the throat to the stomach) is damaged by stomach acid and changed to a lining similar to that of the stomach): 6 people, 54.55%
Stroke (sudden death of a portion of the brain cells due to a lack of oxygen): 2 people, 18.18%
Prostate Cancer: 2 people, 18.18%
Gastric Disorder (disease of stomach): 1 person, 9.09%
Fluid Retention (an abnormal accumulation of fluid in the blood): 1 person, 9.09%

* Approximation only. Some reports may have incomplete information.

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