Emend and Rocephin drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Emend (aprepitant) and Rocephin (ceftriaxone sodium). Common drug interactions include metastases to liver among females and c-reactive protein increased among males.

The phase IV clinical study analyzes what interactions people have when they take Emend and Rocephin. It is created by eHealthMe based on reports of 32 people who take the same drugs from the FDA, and is updated regularly.

What is Emend?

Emend has active ingredients of aprepitant. It is often used in nausea. eHealthMe is studying from 13,741 Emend users. Check the latest studies of Emend.

What is Rocephin?

Rocephin has active ingredients of ceftriaxone sodium. It is often used in infection. eHealthMe is studying from 15,665 Rocephin users. Check the latest studies of Rocephin.

On Aug, 04, 2026

32 people who take Emend and Rocephin together, and have interactions are studied.

What are the common drug interactions of Emend and Rocephin, by gender? *:

female:

Metastases to liver (cancer spreads to liver)
Mucosal inflammation (infection of mucous membrane)
Neutropenia (an abnormally low number of neutrophils)
Obstructive airways disorder (a progressive disease that makes it hard to breathe)
Oedema peripheral (superficial swelling)
Oliguria (not enough urine)
Pleural effusion (water on the lungs)
Pulmonary haemorrhage (acute bleeding from the lung)
Pulmonary mass
Respiratory distress (difficulty in breathing)

male:

C-reactive protein increased
Pleurisy (inflammation of the pleurae, which causes pain when breathing)
Large intestine perforation (hole in large intestine)
Localised infection (infection at the single location)
Oral infection
Pain
Polyp
Thrombosis (formation of a blood clot inside a blood vessel)
Empyema (collection of pus in a cavity in the body)
Fistula (an abnormal connection or passageway between two)

What are the common drug interactions of Emend and Rocephin, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

Dyspnoea (difficult or laboured respiration)

40-49:

Abdominal pain
Alanine aminotransferase increased
Aspartate aminotransferase increased
Constipation
Cough
Haematuria (presence of blood in urine)
Haemoptysis (blood-stained sputum from the bronchi, larynx, trachea, or lungs)
Myalgia (muscle pain)
Oropharyngeal pain
Platelet count decreased

50-59:

Diarrhoea
Polyarthritis (arthritis which involves 5 or more joints simultaneously)
Vomiting

60+:

C-reactive protein increased
Pleurisy (inflammation of the pleurae, which causes pain when breathing)
Colon cancer
Diarrhoea
Dizziness
Intestinal perforation (complete penetration of the wall of the intestine)
Large intestine perforation (hole in large intestine)
Localised infection (infection at the single location)
Lung disorder (lung disease)
Oral infection

What are the existing conditions these people have? *

Fever: 7 people, 21.88%
Nausea And Vomiting: 6 people, 18.75%
Insomnia (sleeplessness): 6 people, 18.75%
Breast Cancer: 5 people, 15.62%
Constipation: 5 people, 15.62%
Urinary Tract Infection: 4 people, 12.50%
Cough: 4 people, 12.50%
Diarrhea: 4 people, 12.50%
Appetite - Decreased (decreased appetite occurs when you have a reduced desire to eat): 4 people, 12.50%
Urination - Painful: 4 people, 12.50%

* Approximation only. Some reports may have incomplete information.

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