Emgality and Amitriptyline hydrochloride drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Emgality (galcanezumab-gnlm) and Amitriptyline hydrochloride (amitriptyline hydrochloride). Common drug interactions include pain in extremity among females and erectile dysfunction among males.

The phase IV clinical study analyzes what interactions people have when they take Emgality and Amitriptyline hydrochloride. It is created by eHealthMe based on reports of 52 people who take the same drugs from the FDA, and is updated regularly.

What is Emgality?

Emgality has active ingredients of galcanezumab-gnlm. eHealthMe is studying from 24,702 Emgality users. Check the latest studies of Emgality.

What is Amitriptyline hydrochloride?

Amitriptyline hydrochloride has active ingredients of amitriptyline hydrochloride. It is often used in migraine. eHealthMe is studying from 20,054 Amitriptyline hydrochloride users. Check the latest studies of Amitriptyline hydrochloride.

On Jul, 12, 2026

52 people who take Emgality and Amitriptyline hydrochloride together, and have interactions are studied.

Emgality and Amitriptyline hydrochloride drug interactions.

What are the common drug interactions of Emgality and Amitriptyline Hydrochloride, by gender? *:

female:

Pain in extremity
Upper respiratory tract infection
Fall
Asthma
Cough
Drug ineffective
Infusion site erythema (reddening of the skin at infusion site)
Infusion site pain
Pruritus (severe itching of the skin)
Urinary tract infection

male:

Erectile dysfunction
Drug ineffective
Renal infarct (kidney damage due to lack of blood supply)

What are the common drug interactions of Emgality and Amitriptyline Hydrochloride, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

Aphonia (inability to produce voice)
Asthma
Bronchitis (inflammation of the mucous membrane in the bronchial tubes)
Fatigue (feeling of tiredness)
Headache (pain in head)
Multiple allergies (allergy to multiple agents)
Musculoskeletal discomfort (discomfort in the body's muscles, joints, tendons, ligaments and nerves)
Nausea (feeling of having an urge to vomit)
Pruritus (severe itching of the skin)
Sinusitis (inflammation of sinus)

30-39:

Gastric perforation (hole in stomach)
Injection site mass
Atrial fibrillation (fibrillation of the muscles of the atria of the heart)
Constipation
Drug ineffective
Haemorrhoids (a swollen vein or group of veins in the region of the anus)
Nausea (feeling of having an urge to vomit)
Vomiting
Aura
Cerebellar infarction (impaired blood circulation to cerebellum)

40-49:

Weight decreased
Weight fluctuation
Nausea (feeling of having an urge to vomit)
Systemic lupus erythematosus (an autoimmune disease, which means the body's immune system mistakenly, attacks healthy tissue)
Alopecia areata (patchy baldness that typically begins with rapid hair loss)
Conjunctival hyperaemia (congestion of conjunctival vessels)
Dysphagia (a condition in which swallowing is difficult or painful)
Lymphadenopathy (disease or enlargement of lymph nodes)
Renal infarct (kidney damage due to lack of blood supply)
Erectile dysfunction

50-59:

Pain in extremity
Fall
Headache (pain in head)
Hypoaesthesia (reduced sense of touch or sensation)
Infusion site erythema (reddening of the skin at infusion site)
Infusion site extravasation (flow of (blood or lymph) from infusion site)
Infusion site pain
Lymph node pain
Lymphadenopathy (disease or enlargement of lymph nodes)
Nasal congestion (blockage of the nasal passages usually due to membranes lining the nose becoming swollen from inflamed blood vessels)

60+:

n/a

What are the existing conditions these people have? *

Multiple Sclerosis (a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath): 9 people, 17.31%
Immunodeficiency Common Variable: 8 people, 15.38%
Asthma: 5 people, 9.62%
Primary Immunodeficiency Syndrome: 4 people, 7.69%
Primary Pulmonary Hypertension (primary high blood pressure that affects the arteries in the lungs and the right side of your heart): 3 people, 5.77%
Nausea (feeling of having an urge to vomit): 3 people, 5.77%

* Approximation only. Some reports may have incomplete information.

Do you take Emgality and Amitriptyline hydrochloride?

- Personalize this study to your gender, age, symptoms and drugs
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously