Emgality and Vyvanse drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Emgality (galcanezumab-gnlm) and Vyvanse (lisdexamfetamine dimesylate). Common drug interactions include blood potassium decreased among females and headache among males.

The phase IV clinical study analyzes what interactions people have when they take Emgality and Vyvanse. It is created by eHealthMe based on reports of 54 people who take the same drugs from the FDA, and is updated regularly.

What is Emgality?

Emgality has active ingredients of galcanezumab-gnlm. eHealthMe is studying from 24,702 Emgality users. Check the latest studies of Emgality.

What is Vyvanse?

Vyvanse has active ingredients of lisdexamfetamine dimesylate. It is often used in attention deficit hyperactivity disorder. eHealthMe is studying from 35,868 Vyvanse users. Check the latest studies of Vyvanse.

On Jul, 26, 2026

54 people who take Emgality and Vyvanse together, and have interactions are studied.

What are the common drug interactions of Emgality and Vyvanse, by gender? *:

female:

Blood potassium decreased
Cardiac disorder
Carpal tunnel syndrome (nerve compression at wrist results numbness weakness, pain , swelling)
Diabetes mellitus (diabetes, caused by a deficiency of the pancreatic hormone insulin)
Dizziness
Drug hypersensitivity
Dysgeusia (disorder of the sense of taste)
Dysphagia (a condition in which swallowing is difficult or painful)
Dyspnoea (difficult or laboured respiration)
Eye swelling

male:

Headache (pain in head)
Bundle branch block right (absence of transmission of electric impulses from the atrioventricular (av) bundle of his to the right ventricle)
Corneal thinning
Cyclic vomiting syndrome (prolonged episodes of severe nausea, vomiting)
Dehydration (dryness resulting from the removal of water)
Disability
Dry eye (lack of adequate tears)
Dyskinesia (abnormality or impairment of voluntary movement)
Hyposmia (impairment of the sense of smell)
Impaired gastric emptying

What are the common drug interactions of Emgality and Vyvanse, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

Headache (pain in head)
Bundle branch block right (absence of transmission of electric impulses from the atrioventricular (av) bundle of his to the right ventricle)
Sinus arrhythmia (a naturally occurring variation in heart rate that occurs during a breathing cycle)
Radiculopathy (a set of conditions in which one or more nerves is affected and does not work properly)
Anger
Back pain
Cat scratch disease (bacterial infection by cat scratch)
Coma (state of unconsciousness lasting more than six hours)
Constipation
Cyclic vomiting syndrome (prolonged episodes of severe nausea, vomiting)

30-39:

Injection site mass
Drug hypersensitivity
Hypersensitivity
Injection site erythema (redness at injection site)
Injection site pain
Injection site pruritus (severe itching at injection site)
Injection site rash
Injection site swelling
Pruritus (severe itching of the skin)
Urticaria (rash of round, red welts on the skin that itch intensely)

40-49:

Cluster headache (one-sided head pain with tearing)
Seizure (abnormal excessive or synchronous neuronal activity in the brain)
Fatigue (feeling of tiredness)
Diaphragmatic hernia (defect or hole in the diaphragm that allows the abdominal contents to move into the chest cavity)
Migraine (headache)
Decreased appetite
Facial paralysis (loss of function of face muscle)
Hyperhidrosis (abnormally increased sweating)
Memory impairment
Multiple sclerosis relapse (reoccurrence of a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath)

50-59:

Suicide attempt
Disturbance in attention
Fatigue (feeling of tiredness)
Insomnia (sleeplessness)
Abdominal distension
Abdominal pain upper
Apathy
Drug ineffective
Feeling jittery
Headache (pain in head)

60+:

Discomfort
Drug ineffective
Swelling face
Pruritus (severe itching of the skin)
Rash
Stress
Anaphylactic shock (severe and rapid and sometimes fatal hypersensitivity reaction to a substance)
Eye swelling
Feeling hot
Flushing (the warm, red condition of human skin)

What are the existing conditions these people have? *

Migraine (headache): 21 people, 38.89%
Narcolepsy (brain's inability to regulate sleep-wake cycles normally): 17 people, 31.48%
Cataplexy (loss of muscle tone accompanied by full conscious awareness): 15 people, 27.78%
Drowsiness: 10 people, 18.52%
Dermatitis Atopic (inflammatory, chronically relapsing, non-contagious and pruritic skin disorder): 4 people, 7.41%
Stress And Anxiety: 3 people, 5.56%
Psoriatic Arthropathy (inflammation of the skin and joints with kin condition which typically causes patches (plaques) of red, scaly skin to develop): 3 people, 5.56%
Nausea (feeling of having an urge to vomit): 3 people, 5.56%
Headache (pain in head): 3 people, 5.56%
Depression: 3 people, 5.56%

* Approximation only. Some reports may have incomplete information.

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