Emla and Anzemet drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Emla (lidocaine; prilocaine) and Anzemet (dolasetron mesylate). Common drug interactions include malaise among females and pulmonary embolism among males.

The phase IV clinical study analyzes what interactions people have when they take Emla and Anzemet. It is created by eHealthMe based on reports of 24 people who take the same drugs from the FDA, and is updated regularly.

What is Emla?

Emla has active ingredients of lidocaine; prilocaine. eHealthMe is studying from 5,276 Emla users. Check the latest studies of Emla.

What is Anzemet?

Anzemet has active ingredients of dolasetron mesylate. eHealthMe is studying from 2,603 Anzemet users. Check the latest studies of Anzemet.



On Jul, 17, 2026

24 people who take Emla and Anzemet together, and have interactions are studied.

Emla and Anzemet drug interactions.

What are the common drug interactions of Emla and Anzemet, by gender? *:

female:

  1. Malaise (a feeling of general discomfort or uneasiness)
  2. Anaphylactic reaction (serious allergic reaction)
  3. Bradycardia (abnormally slow heart action)
  4. Dizziness
  5. Abdominal pain
  6. Abdominal pain lower
  7. Alopecia (absence of hair from areas of the body)
  8. Anaemia (lack of blood)
  9. Anaphylactoid reaction (type of anaphylaxis that does not involve an allergic reaction but is due to direct mast cell degranulation)
  10. Arteriopathic disease (an impairment of the structure or function of the blood vessels which carry blood away from the heart)

male:

  1. Pulmonary embolism (blockage of the main artery of the lung)

What are the common drug interactions of Emla and Anzemet, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

n/a

50-59:

  1. Cardio-respiratory arrest (sudden dysfunction of heart and lungs)
  2. Cyanosis (lack of oxygen in body leads to blue appearance of skin ,mucous membrane nails)
  3. Depressed level of consciousness
  4. Embolism (obstruction of an artery, typically by a clot of blood or an air bubble)
  5. Hypotension (abnormally low blood pressure)
  6. Hypoxia (low oxygen in tissues)
  7. Lymphangitis (inflammation of the lymph channel)
  8. Malaise (a feeling of general discomfort or uneasiness)
  9. Syncope vasovagal (malfunction in the parts of the nervous system leads to consciousness with an inability to maintain postural tone)
  10. Anaphylactic reaction (serious allergic reaction)

60+:

  1. Pulmonary embolism (blockage of the main artery of the lung)
  2. Abdominal pain
  3. Dermatitis acneiform (dermatoses including acne vulgaris, rosacea, folliculitis, and perioral dermatitis)
  4. Diarrhoea
  5. Disease progression
  6. Dry skin
  7. Epistaxis (bleed from the nose)
  8. Erythema (redness of the skin)
  9. Face oedema (swelling of face)
  10. Fatigue (feeling of tiredness)

What are the existing conditions these people have? *

  1. Sleep Disorder: 17 people, 70.83%
  2. Nausea (feeling of having an urge to vomit): 17 people, 70.83%
  3. Muscle Spasms (muscle contraction): 17 people, 70.83%
  4. Hypercalcaemia (elevated calcium (ca+) level in the blood): 17 people, 70.83%
  5. Depression: 17 people, 70.83%
  6. Arthritis (form of joint disorder that involves inflammation of one or more joints): 17 people, 70.83%
  7. Non-Small Cell Lung Cancer Stage Iv: 2 people, 8.33%

* Approximation only. Some reports may have incomplete information.

Do you take Emla and Anzemet?

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Emla and Anzemet:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Emla:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Anzemet:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Emla and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Anzemet and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

How the study uses the data?

The study uses data from the FDA. It is based on lidocaine; prilocaine and dolasetron mesylate (the active ingredients of Emla and Anzemet, respectively), and Emla and Anzemet (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

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