Emla and Valacyclovir hydrochloride drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Emla (lidocaine; prilocaine) and Valacyclovir hydrochloride (valacyclovir hydrochloride). Common drug interactions include cholecystitis chronic among females and gamma-glutamyltransferase increased among males.

The phase IV clinical study analyzes what interactions people have when they take Emla and Valacyclovir hydrochloride. It is created by eHealthMe based on reports of 24 people who take the same drugs from the FDA, and is updated regularly.

What is Emla?

Emla has active ingredients of lidocaine; prilocaine. eHealthMe is studying from 5,276 Emla users. Check the latest studies of Emla.

What is Valacyclovir hydrochloride?

Valacyclovir hydrochloride has active ingredients of valacyclovir hydrochloride. It is often used in herpes zoster. eHealthMe is studying from 12,929 Valacyclovir hydrochloride users. Check the latest studies of Valacyclovir hydrochloride.

On Jul, 09, 2026

24 people who take Emla and Valacyclovir hydrochloride together, and have interactions are studied.

Emla and Valacyclovir hydrochloride drug interactions.

What are the common drug interactions of Emla and Valacyclovir Hydrochloride, by gender? *:

female:

Cholecystitis chronic (long lasting infection of gallbladder)
Breast cancer female
Atrial fibrillation (fibrillation of the muscles of the atria of the heart)
Abdominal pain
Asthenia (weakness)
Hyperthermia (body temperature greatly above normal)
Hypoacusis (loss of hearing)
Neutropenia (an abnormally low number of neutrophils)
White blood cell count decreased
Pyelonephritis (inflammation of kidney caused by bacteria)

male:

Gamma-glutamyltransferase increased
Protein total decreased
Hypoalbuminaemia (levels of albumin in blood serum are abnormally low)
Hypocalcaemia (levels of calcium in blood serum are abnormally low)
Hypomagnesaemia (electrolyte disturbance in which there is an abnormally low level of magnesium in the blood)
Hyponatraemia (abnormally low level of sodium in the blood; associated with dehydration)
Posterior reversible encephalopathy syndrome (posterior reversible encephalopathy syndrome (pres), also known as reversible posterior leukoencephalopathy syndrome (rpls), is a syndrome characterized by headache, confusion, seizures and visual loss)
Pyrexia (fever)
Seizure (abnormal excessive or synchronous neuronal activity in the brain)
Vomiting

What are the common drug interactions of Emla and Valacyclovir Hydrochloride, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

Gamma-glutamyltransferase increased
Protein total decreased
Blood bilirubin increased
Alanine aminotransferase increased
Aspartate aminotransferase increased
Blood alkaline phosphatase increased
Blood albumin decreased
Haematochezia (passage of stools containing blood)
Hyperglycaemia (high blood sugar)
Hypertension (high blood pressure)

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

n/a

50-59:

Cholecystitis chronic (long lasting infection of gallbladder)

60+:

Breast cancer female
Atrial fibrillation (fibrillation of the muscles of the atria of the heart)
Pyelonephritis (inflammation of kidney caused by bacteria)
Alopecia (absence of hair from areas of the body)
Anaemia (lack of blood)
Arthralgia (joint pain)
Blood oestrogen increased
Carpal tunnel syndrome (nerve compression at wrist results numbness weakness, pain , swelling)
Cerebral disorder (brain disease)
Chills (felling of cold)

What are the existing conditions these people have? *

Nausea (feeling of having an urge to vomit): 9 people, 37.50%
Constipation: 8 people, 33.33%
Fever: 7 people, 29.17%
Pain: 7 people, 29.17%
Nausea And Vomiting: 6 people, 25.00%
Multiple Myeloma (cancer of the plasma cells): 6 people, 25.00%
Malignant Histiocytosis (cancerous increase in the number of immune cells): 5 people, 20.83%
Haemorrhage (bleeding): 5 people, 20.83%
Seizures (abnormal excessive or synchronous neuronal activity in the brain): 5 people, 20.83%
Non-Hodgkin's Lymphoma (malignant (cancer) cells form in the lymph system): 4 people, 16.67%

* Approximation only. Some reports may have incomplete information.

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