Emla and Vancomycin drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Emla (lidocaine; prilocaine) and Vancomycin (vancomycin). Common drug interactions include drug hypersensitivity among females and deep vein thrombosis among males.

The phase IV clinical study analyzes what interactions people have when they take Emla and Vancomycin. It is created by eHealthMe based on reports of 36 people who take the same drugs from the FDA, and is updated regularly.

What is Emla?

Emla has active ingredients of lidocaine; prilocaine. eHealthMe is studying from 5,276 Emla users. Check the latest studies of Emla.

What is Vancomycin?

Vancomycin has active ingredients of vancomycin. eHealthMe is studying from 17,165 Vancomycin users. Check the latest studies of Vancomycin.

On Jul, 26, 2026

36 people who take Emla and Vancomycin together, and have interactions are studied.

What are the common drug interactions of Emla and Vancomycin, by gender? *:

female:

Drug hypersensitivity
Cardio-respiratory arrest (sudden dysfunction of heart and lungs)
Pyrexia (fever)
Drug ineffective
Adverse drug reaction
Chronic kidney disease
Hyperparathyroidism secondary (an abnormally high concentration of parathyroid hormone in the blood, resulting in weakening of the bones through loss of calcium-secondary)
Nephrogenic anaemia (anaemia due to kidney disease)
Rash maculo-papular (red area on the skin that is covered with small confluent bumps)
Renal failure (kidney dysfunction)

male:

Deep vein thrombosis (blood clot in a major vein that usually develops in the legs and/or pelvis)
Endocarditis (inflammation in heart muscle)
Streptococcal bacteraemia (a bacterial infection of blood)
Staphylococcal infection (an infection with staphylococcus bacteria)
Anal abscess
Application site pain
Extubation
Mitral valve stenosis (narrowing of mitral valve)
Device occlusion
Device related infection

What are the common drug interactions of Emla and Vancomycin, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

Catheter site infection (infection at the site of insertion)
Staphylococcal infection (an infection with staphylococcus bacteria)

10-19:

Cardio-respiratory arrest (sudden dysfunction of heart and lungs)
Deep vein thrombosis (blood clot in a major vein that usually develops in the legs and/or pelvis)
Endocarditis (inflammation in heart muscle)
Fatigue (feeling of tiredness)
Laryngomalacia (a congenital softening of the tissues of the larynx)
Pericardial effusion (fluid around the heart)
Pneumonia
Pulmonary embolism (blockage of the main artery of the lung)
Respiratory distress (difficulty in breathing)
Respiratory tract oedema (swelling of respiratory tract due to excess fluid collection in tissue)

20-29:

n/a

30-39:

n/a

40-49:

Abscess (pus)
Abscess limb (limb infection)
Anal abscess
Cellulitis (infection under the skin)
Dyspnoea (difficult or laboured respiration)
Genital abscess (build up of pus in genital)
Groin abscess (pus in groin)
Perirectal abscess
Rectal abscess (pus in rectum)
Renal failure (kidney dysfunction)

50-59:

Application site pain
Chronic kidney disease
Hyperparathyroidism secondary (an abnormally high concentration of parathyroid hormone in the blood, resulting in weakening of the bones through loss of calcium-secondary)
Nephrogenic anaemia (anaemia due to kidney disease)
Renal failure (kidney dysfunction)
Diabetic nephropathy (diabetic kidney disease)
Febrile neutropenia (fever with reduced white blood cells)
Gastrooesophageal reflux disease (stomach contents (food or liquid) leak backwards from the stomach into the oesophagus)
Renal injury (kidney injury)
Staphylococcal infection (an infection with staphylococcus bacteria)

60+:

Drug hypersensitivity
Pyrexia (fever)
Acute myocardial infarction (acute heart attack)
Acute respiratory failure
Adrenal insufficiency (a condition in which the adrenal glands do not produce adequate amounts of steroids)
Anaemia (lack of blood)
Anal abscess
Autoimmune hepatitis
Chronic kidney disease
Clostridium difficile colitis (inflammation of colon by clostridium difficile bacteria infection)

What are the existing conditions these people have? *

Nausea (feeling of having an urge to vomit): 12 people, 33.33%
Depression: 12 people, 33.33%
Pain: 11 people, 30.56%
High Blood Pressure: 8 people, 22.22%
Cough: 7 people, 19.44%
Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 6 people, 16.67%
Infection: 6 people, 16.67%
Short-Bowel Syndrome (a condition in which the body cannot absorb enough fluids and nutrients because part of the small intestine is missing): 6 people, 16.67%
Constipation: 6 people, 16.67%
Sepsis (a severe blood infection that can lead to organ failure and death): 5 people, 13.89%

* Approximation only. Some reports may have incomplete information.

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