Sevoflurane and Angioedema - a phase IV clinical study of FDA data

Summary:

Angioedema is reported as a side effect among people who take Sevoflurane (sevoflurane), especially for people who are male, 60+ old, have been taking the drug for < 1 month also take Ondansetron, and have High blood pressure.

The phase IV clinical study analyzes which people have Angioedema when taking Sevoflurane. It is created by eHealthMe based on reports of 9,502 people who have side effects when taking Sevoflurane from the FDA, and is updated regularly.

What is Sevoflurane?

Sevoflurane has active ingredients of sevoflurane. eHealthMe is studying from 9,513 Sevoflurane users. Check the latest studies of Sevoflurane.

What is Angioedema?

Angioedema (rapid swelling of the dermis) is found to be associated with 1,199 drugs and 2,100 conditions by eHealthMe. Check the latest studies of Angioedema.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.



On Jul, 26, 2026

9,502 people reported to have side effects when taking Sevoflurane.
Among them, 37 people (0.39%) have Angioedema.

Could Sevoflurane cause Angioedema?

Among these 37 people:

How long have people been on Sevoflurane when they have Angioedema? *

  • < 1 month: 100 %
  • 1 - 6 months: 0.0 %
  • 6 - 12 months: 0.0 %
  • 1 - 2 years: 0.0 %
  • 2 - 5 years: 0.0 %
  • 5 - 10 years: 0.0 %
  • 10+ years: 0.0 %

What is the gender of people who have Angioedema when taking Sevoflurane? *

  • female: 38.24 %
  • male: 61.76 %

What is the age of people who have Angioedema when taking Sevoflurane? *

  • 0-1: 8.82 %
  • 2-9: 2.94 %
  • 10-19: 8.82 %
  • 20-29: 8.82 %
  • 30-39: 2.94 %
  • 40-49: 2.94 %
  • 50-59: 23.53 %
  • 60+: 41.18 %

What are other drugs people take besides Sevoflurane? *

  1. Ondansetron: 13 people, 35.14%
  2. Amlodipine: 12 people, 32.43%
  3. Apixaban: 11 people, 29.73%
  4. Tylenol: 11 people, 29.73%
  5. Tamsulosin: 10 people, 27.03%
  6. Propofol: 8 people, 21.62%
  7. Fentanyl: 5 people, 13.51%
  8. Diprivan: 4 people, 10.81%
  9. Rocuronium Bromide: 4 people, 10.81%
  10. Fragmin: 4 people, 10.81%

What are other side effects people have besides Angioedema? *

  1. Macroglossia (large tongue): 10 people, 27.03%
  2. Hypotension (abnormally low blood pressure): 6 people, 16.22%
  3. Heart Disease: 5 people, 13.51%
  4. Nausea And Vomiting: 5 people, 13.51%
  5. Conjunctivitis (pink eye): 4 people, 10.81%
  6. Joint Swelling: 4 people, 10.81%
  7. Muscle Spasms (muscle contraction): 4 people, 10.81%
  8. Cough: 4 people, 10.81%
  9. Nasopharyngitis (inflammation of the nasopharynx): 4 people, 10.81%
  10. Nausea (feeling of having an urge to vomit): 4 people, 10.81%

What are the existing conditions these people have? *

  1. High Blood Pressure: 14 people, 37.84%
  2. General Anaesthesia: 8 people, 21.62%
  3. Anaesthesia: 7 people, 18.92%
  4. Neuromuscular Blockade Reversal: 3 people, 8.11%
  5. Blood Pressure Abnormal: 2 people, 5.41%
  6. Pain: 1 person, 2.70%
  7. Neuromuscular Blockade: 1 person, 2.70%
  8. Nausea (feeling of having an urge to vomit): 1 person, 2.70%
  9. Nasal Septum Deviation (deviated nasal septum): 1 person, 2.70%
  10. Ludwig Angina (a type of cellulitis that involves the floor of the mouth, under the tongue): 1 person, 2.70%

* Approximation only. Some reports may have incomplete information.

Do you take Sevoflurane and have Angioedema?

- Check whether Angioedema is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously



Related studies:

Effectiveness of, long term effects of, and alternative drugs to Sevoflurane:

Angioedema treatments and more:

How severe was Angioedema and when was it recovered:

Expand to all the drugs that have ingredients of sevoflurane:

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Sevoflurane:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Angioedema:

Browse all the conditions that are associated with Angioedema:

Related publications that referenced our studies


How the study uses the data?

The study uses data from the FDA. It is based on sevoflurane (the active ingredients of Sevoflurane) and Sevoflurane (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



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