Enablex and Abilify drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Enablex (darifenacin hydrobromide) and Abilify (aripiprazole). Common drug interactions include transient ischaemic attack among females and alanine aminotransferase increased among males.

The phase IV clinical study analyzes what interactions people have when they take Enablex and Abilify. It is created by eHealthMe based on reports of 34 people who take the same drugs from the FDA, and is updated regularly.

What is Enablex?

Enablex has active ingredients of darifenacin hydrobromide. It is often used in urge incontinence. eHealthMe is studying from 4,934 Enablex users. Check the latest studies of Enablex.

What is Abilify?

Abilify has active ingredients of aripiprazole. It is often used in depression. eHealthMe is studying from 101,454 Abilify users. Check the latest studies of Abilify.

On Jul, 20, 2026

34 people who take Enablex and Abilify together, and have interactions are studied.

What are the common drug interactions of Enablex and Abilify, by gender? *:

female:

Transient ischaemic attack (a transient episode of neurologic dysfunction caused by ischemia (loss of blood flow))
Tremor (trembling or shaking movements in one or more parts of your body)
Urinary tract infection
Urticaria (rash of round, red welts on the skin that itch intensely)
Vertigo
White blood cell count increased
Headache (pain in head)
Asthenia (weakness)
Convulsion (muscles contract and relax rapidly and repeatedly, resulting in an uncontrolled shaking of the body)
Type 2 diabetes mellitus

male:

Alanine aminotransferase increased
Angina unstable (chest pain due to ischemia of the heart muscle- unstable)
Haematochezia (passage of stools containing blood)
Haemorrhoids (a swollen vein or group of veins in the region of the anus)
Hemiparesis (weakness on one side of the body)
Injection site bruising
Mental status changes (general changes in brain function, such as confusion, amnesia (memory loss), loss of alertness, loss of orientation)
Muscle rigidity (muscle stiffness)
Myopathy (a muscular disease in which the muscle fibres do not function)
Oliguria (not enough urine)

What are the common drug interactions of Enablex and Abilify, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

Alanine aminotransferase increased
Aspartate aminotransferase increased
Complex partial seizures (epileptic seizure)
Convulsion (muscles contract and relax rapidly and repeatedly, resulting in an uncontrolled shaking of the body)
Decubitus ulcer (a chronic ulcer of the skin caused by prolonged pressure on it)
Haematochezia (passage of stools containing blood)
Haemorrhoids (a swollen vein or group of veins in the region of the anus)
Hemiparesis (weakness on one side of the body)
Mental status changes (general changes in brain function, such as confusion, amnesia (memory loss), loss of alertness, loss of orientation)
Muscle rigidity (muscle stiffness)

30-39:

Ill-defined disorder
Type 2 diabetes mellitus
Suicide attempt

40-49:

Asthenia (weakness)
Chronic kidney disease
Convulsion (muscles contract and relax rapidly and repeatedly, resulting in an uncontrolled shaking of the body)
Abdominal pain
Acute respiratory failure
Blood pressure decreased
Bradycardia (abnormally slow heart action)
Diabetes mellitus (diabetes, caused by a deficiency of the pancreatic hormone insulin)
Fatigue (feeling of tiredness)
Hyperglycaemia (high blood sugar)

50-59:

Fall
Hypersensitivity
Multiple sclerosis (a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath)
Pain in extremity
Asthenia (weakness)
Balance disorder
Decreased activity
Depressed mood
Dizziness
Drug ineffective

60+:

Abdominal discomfort
Alopecia (absence of hair from areas of the body)
Nausea (feeling of having an urge to vomit)
Neutrophil count decreased (less than normal number of neutrophil a type of blood cell)
Pneumonia
Psychological trauma
Psychotic disorder
Sinus congestion (blockage of sinus)
Throat irritation
Tremor (trembling or shaking movements in one or more parts of your body)

What are the existing conditions these people have? *

Multiple Sclerosis (a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath): 11 people, 32.35%
Stress And Anxiety: 5 people, 14.71%
Pain: 5 people, 14.71%
Bipolar Disorder (mood disorder): 4 people, 11.76%
Insomnia (sleeplessness): 3 people, 8.82%
High Blood Cholesterol: 3 people, 8.82%
Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 3 people, 8.82%
Schizophrenia (a mental disorder characterized by a breakdown of thought processes): 2 people, 5.88%
Psychotic Disorder: 2 people, 5.88%
Migraine (headache): 2 people, 5.88%

* Approximation only. Some reports may have incomplete information.

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