Enablex and Adderall drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Enablex (darifenacin hydrobromide) and Adderall (amphetamine aspartate; amphetamine sulfate; dextroamphetamine saccharate; dextroamphetamine sulfate). Common drug interactions include vomiting among females and asthenia among males.

The phase IV clinical study analyzes what interactions people have when they take Enablex and Adderall. It is created by eHealthMe based on reports of 48 people who take the same drugs from the FDA, and is updated regularly.

What is Enablex?

Enablex has active ingredients of darifenacin hydrobromide. It is often used in urge incontinence. eHealthMe is studying from 4,934 Enablex users. Check the latest studies of Enablex.

What is Adderall?

Adderall has active ingredients of amphetamine aspartate; amphetamine sulfate; dextroamphetamine saccharate; dextroamphetamine sulfate. It is often used in attention deficit hyperactivity disorder. eHealthMe is studying from 64,224 Adderall users. Check the latest studies of Adderall.

On Jul, 10, 2026

48 people who take Enablex and Adderall together, and have interactions are studied.

What are the common drug interactions of Enablex and Adderall, by gender? *:

female:

Vomiting
Urinary tract infection
Cystitis interstitial (unknown cause characterized by bladder pain)
Mental status changes (general changes in brain function, such as confusion, amnesia (memory loss), loss of alertness, loss of orientation)
Neuralgia (pain in one or more nerves)
Pelvic pain
Pollakiuria (abnormally frequent passage of relatively small quantities or urine)
Poor quality sleep
Therapeutic response decreased (less preventive response)
Urinary retention (the inability to completely or partially empty the bladder)

male:

Asthenia (weakness)
Dysarthria (speech disorder)
Fatigue (feeling of tiredness)
Pruritus (severe itching of the skin)
Rash
Vision blurred

What are the common drug interactions of Enablex and Adderall, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

Adjustment disorder
Wrist surgery

20-29:

n/a

30-39:

Flushing (the warm, red condition of human skin)
Abdominal discomfort
Dehydration (dryness resulting from the removal of water)
Faecal incontinence (a lack of control over passing stool)
Multiple sclerosis relapse (reoccurrence of a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath)
Rash
Abdominal pain
Body temperature increased
Constipation
Hypoaesthesia (reduced sense of touch or sensation)

40-49:

Urinary tract infection
Mental status changes (general changes in brain function, such as confusion, amnesia (memory loss), loss of alertness, loss of orientation)
Abnormal behaviour
Blood potassium decreased
Blood thyroid stimulating hormone decreased
Clostridium difficile colitis (inflammation of colon by clostridium difficile bacteria infection)
Confusional state
Dehydration (dryness resulting from the removal of water)
Depressed mood
Dyspepsia (indigestion)

50-59:

Hydronephrosis (water inside the kidney)
Hypocalcaemia (levels of calcium in blood serum are abnormally low)
Hypokalaemia (low potassium)
Kidney infection
Leukocytosis (increased white blood cells)
Multiple sclerosis (a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath)
Multiple sclerosis relapse (reoccurrence of a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath)
Myocardial ischaemia (the blood flow through one or more of the blood vessels that lead to heart (coronary arteries) is decreased)
Nephrolithiasis (calculi in the kidneys)
Pyelonephritis (inflammation of kidney caused by bacteria)

60+:

Alanine aminotransferase increased
Aspartate aminotransferase increased
Lung carcinoma cell type unspecified stage iii (the lung cancer has spread to nearby tissue or too far away lymph nodes)

What are the existing conditions these people have? *

Multiple Sclerosis (a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath): 26 people, 54.17%
Narcolepsy (brain's inability to regulate sleep-wake cycles normally): 10 people, 20.83%
Depression: 7 people, 14.58%
Cataplexy (loss of muscle tone accompanied by full conscious awareness): 7 people, 14.58%
Stress And Anxiety: 6 people, 12.50%
Pain: 6 people, 12.50%
Headache (pain in head): 5 people, 10.42%
Insomnia (sleeplessness): 4 people, 8.33%
Memory Loss: 3 people, 6.25%
Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 3 people, 6.25%

* Approximation only. Some reports may have incomplete information.

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