Enbrel and Theo-dur drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Enbrel (etanercept) and Theo-dur (theophylline). Common drug interactions include inflammation among females and aphasia among males.

The phase IV clinical study analyzes what interactions people have when they take Enbrel and Theo-dur. It is created by eHealthMe based on reports of 26 people who take the same drugs from the FDA, and is updated regularly.

What is Enbrel?

Enbrel has active ingredients of etanercept. It is often used in rheumatoid arthritis. eHealthMe is studying from 664,678 Enbrel users. Check the latest studies of Enbrel.

What is Theo-dur?

Theo-dur has active ingredients of theophylline. It is often used in asthma. eHealthMe is studying from 4,451 Theo-dur users. Check the latest studies of Theo-dur.

On Jul, 16, 2026

26 people who take Enbrel and Theo-dur together, and have interactions are studied.

What are the common drug interactions of Enbrel and Theo-Dur, by gender? *:

female:

Inflammation
Insomnia (sleeplessness)
Intervertebral disc protrusion (spinal disc protrusion)
Intestinal perforation (complete penetration of the wall of the intestine)
Joint effusion (presence of extra fluid in joint covering)
Lipoma excision
Menopause (end of monthly cycles in women)
Movement disorder (neurological syndromes where they may be excess of movement or a paucity of movement that is not connected to weakness)
Neuroma (tumour of nerve tissue)
Neutropenia (an abnormally low number of neutrophils)

male:

Aphasia (damage to the parts of the brain that control language)
Asthenia (weakness)
Respiratory failure (inadequate gas exchange by the respiratory system)
Urinary incontinence (inability to control the flow of urine and involuntary urination)
Loss of consciousness
Myocardial infarction (destruction of heart tissue resulting from obstruction of the blood supply to the heart muscle)
Headache (pain in head)
Influenza like illness
Injection site pain
Nasopharyngitis (inflammation of the nasopharynx)

What are the common drug interactions of Enbrel and Theo-Dur, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

Osteoarthritis (a joint disease caused by cartilage loss in a joint)
Osteoporosis (bones weak and more likely to break)
Paraesthesia (sensation of tingling, tickling, prickling, pricking, or burning of a person's skin with no apparent long-term physical effect)
Patellofemoral pain syndrome (pain in the front of the knee)
Pyrexia (fever)
Radicular syndrome (pain and other symptoms such as numbness, tingling and weakness in the arms or legs)
Renal failure (kidney dysfunction)
Retroperitoneal neoplasm (tumour between peritoneum and the posterior abdominal wall)
Synovitis (inflammation of the synovial membrane)
Tendon operation

50-59:

Myocardial infarction (destruction of heart tissue resulting from obstruction of the blood supply to the heart muscle)
Cardiac failure congestive
Cardiogenic shock (inadequate circulation of blood)
Pneumonia
Abdominal pain upper
Blood creatine phosphokinase increased
Blood creatine phosphokinase mb increased
Blood lactate dehydrogenase increased
Cardiac failure
Cardiac index decreased

60+:

Fatigue (feeling of tiredness)
Chest discomfort
Adenosquamous cell lung cancer stage iv (mixed cell lung cancer stage iv)
Back pain
Death
Decreased appetite
Heart rate increased
Hydropneumothorax (presence of both air and fluid in the pleural space (lungs))
Hypoalbuminaemia (levels of albumin in blood serum are abnormally low)
Metastases to bone (cancer spreads to bone)

What are the existing conditions these people have? *

High Blood Pressure: 8 people, 30.77%
Hypersensitivity: 4 people, 15.38%
Gastritis (inflammation of stomach): 4 people, 15.38%

* Approximation only. Some reports may have incomplete information.

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