Enstilar and Clobex drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Enstilar (betamethasone dipropionate; calcipotriene) and Clobex (clobetasol propionate). Common drug interactions include cholelithiasis among females and psoriatic arthropathy among males.

The phase IV clinical study analyzes what interactions people have when they take Enstilar and Clobex. It is created by eHealthMe based on reports of 23 people who take the same drugs from the FDA, and is updated regularly.

What is Enstilar?

Enstilar has active ingredients of betamethasone dipropionate; calcipotriene. eHealthMe is studying from 1,673 Enstilar users. Check the latest studies of Enstilar.

What is Clobex?

Clobex has active ingredients of clobetasol propionate. It is often used in psoriasis. eHealthMe is studying from 1,447 Clobex users. Check the latest studies of Clobex.

On Jul, 06, 2026

23 people who take Enstilar and Clobex together, and have interactions are studied.

What are the common drug interactions of Enstilar and Clobex, by gender? *:

female:

Cholelithiasis (the presence or formation of gallstones in the gallbladder or bile ducts)
Wound infection
Rash
Rectal haemorrhage (bleeding from anus)
Abdominal discomfort
Asthenia (weakness)
Death
Diabetes mellitus (diabetes, caused by a deficiency of the pancreatic hormone insulin)
Diarrhoea
Dizziness

male:

Psoriatic arthropathy (inflammation of the skin and joints with kin condition which typically causes patches (plaques) of red, scaly skin to develop)
Arthralgia (joint pain)
Eczema (patches of skin become rough and inflamed, with itching and bleeding blisters)
Epistaxis (bleed from the nose)
Hepatic lesion
Hypertension (high blood pressure)
Insomnia (sleeplessness)
Nasopharyngitis (inflammation of the nasopharynx)
Pruritus (severe itching of the skin)
Renal artery stenosis (narrowing of renal artery)

What are the common drug interactions of Enstilar and Clobex, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

Gastroenteritis (inflammation of stomach and intestine)
Pneumonia

40-49:

Alanine aminotransferase increased
Glucose tolerance impaired (blood glucose is raised beyond normal levels, but not high enough to warrant a diabetes diagnosis)

50-59:

n/a

60+:

Pruritus (severe itching of the skin)
Rectal haemorrhage (bleeding from anus)
Renal artery stenosis (narrowing of renal artery)
Rosacea (a skin condition that causes facial redness)
Seborrhoeic dermatitis (a common, inflammatory skin condition that causes flaky, white to yellowish scales to form on oily areas such as the scalp)
Urticaria (rash of round, red welts on the skin that itch intensely)
Asthenia (weakness)
Cardiac arrest
Cholelithiasis (the presence or formation of gallstones in the gallbladder or bile ducts)
Death

What are the existing conditions these people have? *

Arthritis (form of joint disorder that involves inflammation of one or more joints): 2 people, 8.70%

* Approximation only. Some reports may have incomplete information.

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